Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Catalano-Dupuy, D.L.; Musumeci, M.A.; Lopez-Rivero, A.; Ceccarelli, E.A.
    A highly stable plastidic-type ferredoxin-NADP(H) reductase in the pathogenic bacterium Leptospira interrogans (2011), PLoS ONE, 6, e26736.
    View publication on PubMedView publication on EuropePMC

General Stability

EC Number General Stability Organism
1.18.1.2 persistence of a native folded structure is detected in up to 6 M urea, with 38% residual activity, the high stability might be due to robust interactions between the FAD and the NADP+ domains of the protein Leptospira interrogans

Organism

EC Number Organism UniProt Comment Textmining
1.18.1.2 Leptospira interrogans Q8EY89
-
-
1.18.1.2 Leptospira interrogans 56601 Q8EY89
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.18.1.2 2 reduced ferredoxin + NADP+ source of ferredoxin: Leptospira LB107 Leptospira interrogans 2 oxidized ferredoxin + NADPH + H+
-
 ?
1.18.1.2 2 reduced ferredoxin + NADP+ source of ferredoxin: Leptospira LB107 Leptospira interrogans 56601 2 oxidized ferredoxin + NADPH + H+
-
 ?
1.18.1.2 additional information enzyme additionally displays high diaphorase activity using artificial acceptors and functions as a ferric reductase Leptospira interrogans ?
-
 ?
1.18.1.2 additional information enzyme additionally displays high diaphorase activity using artificial acceptors and functions as a ferric reductase Leptospira interrogans 56601 ?
-
 ?

Temperature Stability [°C]

EC Number Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
1.18.1.2 68.1
-
 melting temperature Leptospira interrogans

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.18.1.2 6.5
-
-
 Leptospira interrogans

Cofactor

EC Number Cofactor Comment Organism Structure
1.18.1.2 FAD the high stability of the enzyme might be due to robust interactions between the FAD and the NADP+ domains of the protein Leptospira interrogans
1.18.1.2 NADPH
-
 Leptospira interrogans