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Literature summary extracted from

  • Roy, M.; Sivan-Loukianova, E.; Eberl, D.F.
    Cell-type-specific roles of Na+/K+ ATPase subunits in Drosophila auditory mechanosensation (2013), Proc. Natl. Acad. Sci. USA, 110, 181-186.
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
7.2.2.13 ATP + H2O + Na+/in + K+/out Drosophila melanogaster
-
 ADP + phosphate + Na+/out + K+/in
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
7.2.2.13 Drosophila melanogaster
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
7.2.2.13 Johnston's organ
-
 Drosophila melanogaster
-
7.2.2.13 scolopale cell
-
 Drosophila melanogaster
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
7.2.2.13 ATP + H2O + Na+/in + K+/out
-
 Drosophila melanogaster ADP + phosphate + Na+/out + K+/in
-
 ?

Synonyms

EC Number Synonyms Comment Organism
7.2.2.13 ATPalpha catalytic subunit Drosophila melanogaster
7.2.2.13 Na pump
-
 Drosophila melanogaster
7.2.2.13 Na+/K+-ATPase
-
 Drosophila melanogaster

General Information

EC Number General Information Comment Organism
7.2.2.13 malfunction knocking down of catalytic subunit ATPalpha, but not alpha-like, in the entire Johnston's organ results in complete deafness. Knocking down beta subunit nrv2 in scolopale cells reduces ATPalpha expression in scolopale cells and causes almost complete deafness Drosophila melanogaster
7.2.2.13 physiological function the catalytic subunit ATPalpha is required for hearing Drosophila melanogaster