EC Number | Application | Comment | Organism |
---|---|---|---|
2.3.1.164 | synthesis | strategy to improve penicillin biosynthesis by Penicillium chrysogenum by reducing reactive and toxic metabolic byproducts, 2-oxoaldehydes. This is achieved by overexpressing the genes encoding glyoxalase I and II, which results in a 10% increase in penicillin titers relative to the control strain. The protein levels of isopenicillin N synthase and isopenicillin N acyltransferase are increased in the glyoxalase transformants, whereas their transcript levels remains unaltered | Penicillium chrysogenum |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.3.1.164 | Penicillium chrysogenum | - |
- |
- |
2.3.1.164 | Penicillium chrysogenum DS17690 | - |
- |
- |
EC Number | Organism | Comment | Expression |
---|---|---|---|
2.3.1.164 | Penicillium chrysogenum | in strains overexpressing the genes encoding glyoxalase I and II, the protein levels of isopenicillin N synthase and isopenicillin N acyltransferase are increased | up |