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Literature summary extracted from

  • Wu, W.; Tran-Gyamfi, M.; Jaryenneh, J.; Davis, R.
    Cofactor engineering of ketol-acid reductoisomerase (IlvC) and alcohol dehydrogenase (YqhD) improves the fusel alcohol yield in algal protein anaerobic fermentation (2016), Algal Res., 19, 162-167.
No PubMed abstract available

Application

EC Number Application Comment Organism
1.1.1.383 biofuel production combination of high activity alcohol dehydrogenase YqhD mutants with IlvC mutants, both accepting NADH as a redox cofactor, in an engineered Escherichia coli strain, enabling comprehensive utilization of the biomass for biofuel applications. The refined strain, shows an increased fusel alcohol yield of about 60% compared to wild type under anaerobic fermentation on amino acid mixtures.When applied to real algal protein hydrolysates, the strain produces 100% and 38% more total mixed alcohols than the wild type strain on two different algal hydrolysates, respectively Escherichia coli

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.1.1.383 expression in Escherichia coli Escherichia coli

Protein Variants

EC Number Protein Variants Comment Organism
1.1.1.383 A71S/R76D/S78D/Q110V strain engineered to switch the cofactor specificity fromNADPH to NADH, application in an engineered Escherichia coli strain, enabling comprehensive utilization of the biomass for biofuel applications Escherichia coli

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.383 Escherichia coli P05793
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-

Synonyms

EC Number Synonyms Comment Organism
1.1.1.383 ilvC
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Escherichia coli