BRENDA - Enzyme Database

Promiscuous activity of (S,S)-butanediol dehydrogenase is responsible for glycerol production from 1,3-dihydroxyacetone in Corynebacterium glutamicum under oxygen-deprived conditions

Jojima, T.; Igari, T.; Moteki, Y.; Suda, M.; Yukawa, H.; Inui, M.; Appl. Microbiol. Biotechnol. 99, 1427-1433 (2015)

Data extracted from this reference:

Natural Substrates/ Products (Substrates)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
ID
1.1.1.76
(2S)-acetoin + NADH + H+
Corynebacterium glutamicum
-
(2S,3S)-butane-2,3-diol + NAD+
-
-
r
1.1.1.76
(2S)-acetoin + NADH + H+
Corynebacterium glutamicum JCM 18229
-
(2S,3S)-butane-2,3-diol + NAD+
-
-
r
1.1.1.76
(2S,3S)-butane-2,3-diol + NAD+
Corynebacterium glutamicum
-
(2S)-acetoin + NADH + H+
-
-
r
1.1.1.76
(2S,3S)-butane-2,3-diol + NAD+
Corynebacterium glutamicum JCM 18229
-
(2S)-acetoin + NADH + H+
-
-
r
Organism
EC Number
Organism
UniProt
Commentary
Textmining
1.1.1.76
Corynebacterium glutamicum
-
-
-
1.1.1.76
Corynebacterium glutamicum JCM 18229
-
-
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
Substrate Product ID
1.1.1.76
(2S)-acetoin + NADH + H+
-
737540
Corynebacterium glutamicum
(2S,3S)-butane-2,3-diol + NAD+
-
-
-
r
1.1.1.76
(2S)-acetoin + NADH + H+
-
737540
Corynebacterium glutamicum JCM 18229
(2S,3S)-butane-2,3-diol + NAD+
-
-
-
r
1.1.1.76
(2S,3S)-butane-2,3-diol + NAD+
-
737540
Corynebacterium glutamicum
(2S)-acetoin + NADH + H+
-
-
-
r
1.1.1.76
(2S,3S)-butane-2,3-diol + NAD+
-
737540
Corynebacterium glutamicum JCM 18229
(2S)-acetoin + NADH + H+
-
-
-
r
1.1.1.76
1,3-dihydroxyacetone + NADH + H+
low activity with 30 mM
737540
Corynebacterium glutamicum
?
-
-
-
?
1.1.1.76
1,3-dihydroxyacetone + NADH + H+
low activity with 30 mM
737540
Corynebacterium glutamicum JCM 18229
?
-
-
-
?
1.1.1.76
glyceraldehyde + NADH + H+
low activity with 30 mM
737540
Corynebacterium glutamicum
?
-
-
-
?
1.1.1.76
glyceraldehyde + NADH + H+
low activity with 30 mM
737540
Corynebacterium glutamicum JCM 18229
?
-
-
-
?
Synonyms
EC Number
Synonyms
Commentary
Organism
1.1.1.76
(S,S)-2,3-butanediol dehydrogenase
-
Corynebacterium glutamicum
1.1.1.76
(S,S)-butanediol dehydrogenase
-
Corynebacterium glutamicum
1.1.1.76
BDH
-
Corynebacterium glutamicum
1.1.1.76
ButA
-
Corynebacterium glutamicum
Cofactor
EC Number
Cofactor
Commentary
Organism
Structure
1.1.1.76
NAD+
-
Corynebacterium glutamicum
Cofactor (protein specific)
EC Number
Cofactor
Commentary
Organism
Structure
1.1.1.76
NAD+
-
Corynebacterium glutamicum
Natural Substrates/ Products (Substrates) (protein specific)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
ID
1.1.1.76
(2S)-acetoin + NADH + H+
Corynebacterium glutamicum
-
(2S,3S)-butane-2,3-diol + NAD+
-
-
r
1.1.1.76
(2S)-acetoin + NADH + H+
Corynebacterium glutamicum JCM 18229
-
(2S,3S)-butane-2,3-diol + NAD+
-
-
r
1.1.1.76
(2S,3S)-butane-2,3-diol + NAD+
Corynebacterium glutamicum
-
(2S)-acetoin + NADH + H+
-
-
r
1.1.1.76
(2S,3S)-butane-2,3-diol + NAD+
Corynebacterium glutamicum JCM 18229
-
(2S)-acetoin + NADH + H+
-
-
r
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
ID
1.1.1.76
(2S)-acetoin + NADH + H+
-
737540
Corynebacterium glutamicum
(2S,3S)-butane-2,3-diol + NAD+
-
-
-
r
1.1.1.76
(2S)-acetoin + NADH + H+
-
737540
Corynebacterium glutamicum JCM 18229
(2S,3S)-butane-2,3-diol + NAD+
-
-
-
r
1.1.1.76
(2S,3S)-butane-2,3-diol + NAD+
-
737540
Corynebacterium glutamicum
(2S)-acetoin + NADH + H+
-
-
-
r
1.1.1.76
(2S,3S)-butane-2,3-diol + NAD+
-
737540
Corynebacterium glutamicum JCM 18229
(2S)-acetoin + NADH + H+
-
-
-
r
1.1.1.76
1,3-dihydroxyacetone + NADH + H+
low activity with 30 mM
737540
Corynebacterium glutamicum
?
-
-
-
?
1.1.1.76
1,3-dihydroxyacetone + NADH + H+
low activity with 30 mM
737540
Corynebacterium glutamicum JCM 18229
?
-
-
-
?
1.1.1.76
glyceraldehyde + NADH + H+
low activity with 30 mM
737540
Corynebacterium glutamicum
?
-
-
-
?
1.1.1.76
glyceraldehyde + NADH + H+
low activity with 30 mM
737540
Corynebacterium glutamicum JCM 18229
?
-
-
-
?