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Literature summary extracted from

  • Almeida, J.; Azevedo, M.d.a..S.; Spicher, L.; Glauser, G.; vom Dorp, K.; Guyer, L.; del Valle Carranza, A.; Asis, R.; de Souza, A.P.; Buckeridge, M.; Demarco, D.; Bres, C.; Rothan, C.; Peres, L.E.; Hoertensteiner, S.; Kessler, F.; Doermann, P.; Carrari, F.; Rossi, M.
    Down-regulation of tomato phytol kinase strongly impairs tocopherol biosynthesis and affects prenyllipid metabolism in an organ-specific manner (2016), J. Exp. Bot., 67, 919-934.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.7.1.182 gene VTE5, genotyping, identification of enzyme-deficient mutants, phylogenetic analysis Solanum lycopersicum

Protein Variants

EC Number Protein Variants Comment Organism
2.7.1.182 additional information generation of SlVTE5-RNAi transgenic lines, RNAi-mediated silencing of the Solyc03g071720 locus using primers RNAi-VTE5-F and RNAi-VTE5-R. TILLING-based molecular screening is used to identify a loss-offunction mutation in SlFOLK using an EMS-mutagenized tomato collection Solanum lycopersicum

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.1.182 CTP + phytol Solanum lycopersicum
-
 CDP + phytyl phosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.1.182 Solanum lycopersicum A0A3Q7FJ72 cv. Micro-Tom
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.1.182 fruit mature green and ripe Solanum lycopersicum
-
2.7.1.182 leaf
-
 Solanum lycopersicum
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.1.182 CTP + phytol
-
 Solanum lycopersicum CDP + phytyl phosphate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.1.182 phytol kinase
-
 Solanum lycopersicum
2.7.1.182 SlVTE5
-
 Solanum lycopersicum
2.7.1.182 VTE5
-
 Solanum lycopersicum

Cofactor

EC Number Cofactor Comment Organism Structure
2.7.1.182 CTP
-
 Solanum lycopersicum

General Information

EC Number General Information Comment Organism
2.7.1.182 malfunction downregulation of tomato phytol kinase strongly impairs tocopherol biosynthesis and affects prenyllipid metabolism in an organ-specific manner. VTE5-deficient plants display starch accumulation and lower CO2 assimilation in leaves associated with mild yield penalty. Carbohydrate export blockage in the VTE5-deficient plants affecting tomato fruit quality. Chlorophyll content is not affected in SlVTE5-RNAi lines. Phenotype, overview Solanum lycopersicum
2.7.1.182 metabolism the enzyme is essential in tocopherol biosynthesis, tocopherol biosynthetic and related pathways, overview Solanum lycopersicum
2.7.1.182 physiological function chlorophyll phytol tail recycling depends on phytol kinase activity. Phytol diphosphate is required for synthesis of tocopherol involving the condensation with an aromatic head group Solanum lycopersicum