EC Number | Cloned (Comment) | Organism |
---|---|---|
2.8.3.5 | expressed in Escherichia coli BL21(DE3) cells | Homo sapiens |
EC Number | Crystallization (Comment) | Organism |
---|---|---|
2.8.3.5 | sitting drop vapor diffusion method, using 0.20 M sodium chloride, 0.1 M Tris pH 9.0 and 25% (w/v) polyethylene glycol 3350 | Homo sapiens |
EC Number | Protein Variants | Comment | Organism |
---|---|---|---|
2.8.3.5 | A215V | the mutation is associated with succinyl-CoA:3-ketoacid CoA transferase deficiency | Homo sapiens |
2.8.3.5 | C456F | the mutation is associated with succinyl-CoA:3-ketoacid CoA transferase deficiency | Homo sapiens |
2.8.3.5 | E273X | the mutation is associated with succinyl-CoA:3-ketoacid CoA transferase deficiency | Homo sapiens |
2.8.3.5 | G219E | the mutation is associated with succinyl-CoA:3-ketoacid CoA transferase deficiency | Homo sapiens |
2.8.3.5 | G324E | the mutation is associated with succinyl-CoA:3-ketoacid CoA transferase deficiency | Homo sapiens |
2.8.3.5 | L327P | the mutation is associated with succinyl-CoA:3-ketoacid CoA transferase deficiency | Homo sapiens |
2.8.3.5 | L429F | the mutation is associated with succinyl-CoA:3-ketoacid CoA transferase deficiency | Homo sapiens |
2.8.3.5 | M388V | the mutation is associated with succinyl-CoA:3-ketoacid CoA transferase deficiency | Homo sapiens |
2.8.3.5 | P262R | the mutation is associated with succinyl-CoA:3-ketoacid CoA transferase deficiency | Homo sapiens |
2.8.3.5 | R217X | the mutation is associated with succinyl-CoA:3-ketoacid CoA transferase deficiency | Homo sapiens |
2.8.3.5 | R268C | the mutation is associated with succinyl-CoA:3-ketoacid CoA transferase deficiency | Homo sapiens |
2.8.3.5 | R268H | the mutation is associated with succinyl-CoA:3-ketoacid CoA transferase deficiency | Homo sapiens |
2.8.3.5 | R38C | the mutation is associated with succinyl-CoA:3-ketoacid CoA transferase deficiency | Homo sapiens |
2.8.3.5 | R468C | the mutation is associated with succinyl-CoA:3-ketoacid CoA transferase deficiency | Homo sapiens |
2.8.3.5 | S226N | the mutation is associated with succinyl-CoA:3-ketoacid CoA transferase deficiency | Homo sapiens |
2.8.3.5 | S283X | the mutation is associated with succinyl-CoA:3-ketoacid CoA transferase deficiency | Homo sapiens |
2.8.3.5 | S405P | the mutation is associated with succinyl-CoA:3-ketoacid CoA transferase deficiency | Homo sapiens |
2.8.3.5 | T435N | the mutation is associated with succinyl-CoA:3-ketoacid CoA transferase deficiency | Homo sapiens |
2.8.3.5 | V112D | the mutation is associated with succinyl-CoA:3-ketoacid CoA transferase deficiency | Homo sapiens |
2.8.3.5 | V133E | the mutation is associated with succinyl-CoA:3-ketoacid CoA transferase deficiency | Homo sapiens |
2.8.3.5 | V221M | the mutation is associated with succinyl-CoA:3-ketoacid CoA transferase deficiency | Homo sapiens |
2.8.3.5 | V404F | the mutation is associated with succinyl-CoA:3-ketoacid CoA transferase deficiency | Homo sapiens |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
2.8.3.5 | mitochondrion | - |
Homo sapiens | 5739 | - |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.8.3.5 | Homo sapiens | P55809 | - |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
2.8.3.5 | HisTrap column chromatography, and Superdex 200 gel filtration | Homo sapiens |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.8.3.5 | succinyl-CoA + acetoacetate | - |
Homo sapiens | succinate + acetoacetyl-CoA | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
2.8.3.5 | homodimer | x-ray crystallography | Homo sapiens |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.8.3.5 | 3-oxoacid CoA transferase 1 | - |
Homo sapiens |
2.8.3.5 | OXCT1 | - |
Homo sapiens |
2.8.3.5 | SCOT | - |
Homo sapiens |
2.8.3.5 | succinyl-CoA:3-ketoacid CoA transferase | - |
Homo sapiens |