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Literature summary extracted from

  • Ahmed, F.H.; Mohamed, A.E.; Carr, P.D.; Lee, B.M.; Condic-Jurkic, K.; O'Mara, M.L.; Jackson, C.J.
    Rv2074 is a novel F420H2-dependent biliverdin reductase in Mycobacterium tuberculosis (2016), Protein Sci., 25, 1692-1709.
    View publication on PubMedView publication on EuropePMC

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
1.3.1.24 hanging drop vapor diffusion method, using 27% (w/v) PEG 3350, 0.2M MgCl2 and 0.1 M BisTris at pH 5.5 Mycobacterium tuberculosis

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.3.1.24 biliverdin + coenzyme F420 + H+ Mycobacterium tuberculosis
-
 bilirubin + reduced coenzyme F420
-
 ?
1.3.1.24 biliverdin + coenzyme F420 + H+ Mycobacterium tuberculosis H37Rv
-
 bilirubin + reduced coenzyme F420
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.3.1.24 Mycobacterium tuberculosis
-
-
-
1.3.1.24 Mycobacterium tuberculosis H37Rv
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.3.1.24 Ni-NTA resin column chromatography, HisTrap column chromatography and Superdex 75 gel filtration Mycobacterium tuberculosis

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.3.1.24 biliverdin + coenzyme F420 + H+
-
 Mycobacterium tuberculosis bilirubin + reduced coenzyme F420
-
 ?
1.3.1.24 biliverdin + coenzyme F420 + H+
-
 Mycobacterium tuberculosis H37Rv bilirubin + reduced coenzyme F420
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.3.1.24 F-BVR
-
 Mycobacterium tuberculosis
1.3.1.24 F420H2-dependent biliverdin reductase
-
 Mycobacterium tuberculosis
1.3.1.24 Rv2074
-
 Mycobacterium tuberculosis

Cofactor

EC Number Cofactor Comment Organism Structure
1.3.1.24 coenzyme F420
-
 Mycobacterium tuberculosis