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Literature summary extracted from

  • Pietra, F.
    On the quest of dioxygen by monomeric sarcosine oxidase. A molecular dynamics investigation (2015), Chem. Biodivers., 12, 1163-1171 .
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.5.3.1 Furoic acid
-
 Bacillus sp. BSD-8

Organism

EC Number Organism UniProt Comment Textmining
1.5.3.1 Bacillus sp. BSD-8 Q6ITC6
-
-

Reaction

EC Number Reaction Comment Organism Reaction ID
1.5.3.1 sarcosine + H2O + O2 = glycine + formaldehyde + H2O2 molecular dynamics investigation by random acceleration molecular dynamics simulations with an ensemble made of the bacterial monomeric sarcosine oxidase (2GF3), O2, and the inhibitor furoic acid to mimic sarcosine Bacillus sp. BSD-8
a

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.5.3.1 sarcosine + H2O + O2 molecular dynamics investigation by random acceleration molecular dynamics simulations with an ensemble made of the bacterial monomeric sarcosine oxidase (2GF3), O2, and the inhibitor furoic acid to mimic sarcosine. The ensemble is solvated by in a periodic box, while an external tiny force acts randomly to expel O2 from the center of activation, located between residue K265 and the si face of the flavin ring of the flavin adenine dinucleotide cofactor, moving it toward the solvent Bacillus sp. BSD-8 glycine + formaldehyde + H2O2
-
 ?

Subunits

EC Number Subunits Comment Organism
1.5.3.1 monomer 1 * 43182, calculated from sequence Bacillus sp. BSD-8

Synonyms

EC Number Synonyms Comment Organism
1.5.3.1 MSOX
-
 Bacillus sp. BSD-8