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Literature summary extracted from

  • Yue, Y.; Liu, J.; He, C.
    RNA N6-methyladenosine methylation in post-transcriptional gene expression regulation (2015), Genes Dev., 29, 1343-1355 .
    View publication on PubMedView publication on EuropePMC

Organism

EC Number Organism UniProt Comment Textmining
2.1.1.348 Arabidopsis thaliana
-
-
-
2.1.1.348 Danio rerio
-
-
-
2.1.1.348 Drosophila melanogaster
-
-
-
2.1.1.348 Mus musculus
-
-
-
2.1.1.348 Saccharomyces cerevisiae
-
-
-

Synonyms

EC Number Synonyms Comment Organism
2.1.1.348 ALKBH5
-
 Mus musculus
2.1.1.348 FTO
-
 Mus musculus
2.1.1.348 IME4
-
 Drosophila melanogaster
2.1.1.348 IME4
-
 Saccharomyces cerevisiae
2.1.1.348 METTL14
-
 Mus musculus
2.1.1.348 METTL14
-
 Danio rerio
2.1.1.348 METTL3
-
 Mus musculus
2.1.1.348 METTL3
-
 Danio rerio
2.1.1.348 MTA
-
 Arabidopsis thaliana
2.1.1.348 YTHDF2
-
 Mus musculus

General Information

EC Number General Information Comment Organism
2.1.1.348 malfunction depletion of isoforms METTL3 and METTL14 leads to apoptosis in cancer cells Mus musculus
2.1.1.348 physiological function isoforms METTL3 and METTL4 are required for normal embryogenesis Danio rerio
2.1.1.348 physiological function isoforms METTL3 and METTL4 regulate stem cell differentiation and reprogramming. Isoform METTL3 regulates circadian periods Mus musculus
2.1.1.348 physiological function the enzyme is essential for viability and required for Notch signaling during oogenesis Drosophila melanogaster
2.1.1.348 physiological function the enzyme is required for embryonic development , normal growth patterns, apical dominance, and plant development Arabidopsis thaliana
2.1.1.348 physiological function the enzyme is required for meiosis and sporulation Saccharomyces cerevisiae