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Literature summary extracted from

  • Bouwmeester, H.; Konings, M.; Gershenzon, J.; Karp, F.; Croteau, R.
    Cytochrome P-450 dependent (+)-limonene-6-hydroxylation in fruits of caraway (Carum carvi) (1999), Phytochemistry, 50, 243-248 .
No PubMed abstract available

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.14.14.51 clotrimazole
-
 Carum carvi
1.14.14.51 CO
-
 Carum carvi
1.14.14.51 cytochrome c
-
 Carum carvi
1.14.14.51 Metyrapone
-
 Carum carvi
1.14.14.51 miconazole
-
 Carum carvi
1.14.14.51 additional information blue light strongly decreases enzyme activity Carum carvi

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.14.14.51 microsome
-
 Carum carvi
-
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.14.14.51 (S)-limonene + [reduced NADPH-hemoprotein reductase] + O2 Carum carvi
-
 (-)-trans-carveol + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.14.14.51 Carum carvi
-
 variant Karzo
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.14.14.51 fruit
-
 Carum carvi
-

Storage Stability

EC Number Storage Stability Organism
1.14.14.51 -80°C, enzyme in microsomal pellet, over 1 year, no loss of activity Carum carvi

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.14.51 (S)-limonene + [reduced NADPH-hemoprotein reductase] + O2
-
 Carum carvi (-)-trans-carveol + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.14.14.51 (+)-limonene-6-hydroxylase
-
 Carum carvi

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.14.14.51 6.3 8.4 half-maximal activities at pH 6.3 and 8.4 Carum carvi

Cofactor

EC Number Cofactor Comment Organism Structure
1.14.14.51 FAD
-
 Carum carvi
1.14.14.51 FMN
-
 Carum carvi
1.14.14.51 NADPH
-
 Carum carvi