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Literature summary extracted from

  • Brychkova, G.; Yarmolinsky, D.; Batushansky, A.; Grishkevich, V.; Khozin-Goldberg, I.; Fait, A.; Amir, R.; Fluhr, R.; Sagi, M.
    Sulfite oxidase activity is essential for normal sulfur, nitrogen and carbon metabolism in tomato leaves (2015), Plants (Basel), 4, 573-605 .
    View publication on PubMedView publication on EuropePMC

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.8.3.1 peroxisome
-
 Solanum lycopersicum 5777
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
1.8.3.1 Molybdenum in the molybdenum cofactor Solanum lycopersicum

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.8.3.1 sulfite + O2 + H2O Solanum lycopersicum
-
 sulfate + H2O2
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.8.3.1 Solanum lycopersicum
-
 cv. Rheinlands Ruhm
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.8.3.1 leaf
-
 Solanum lycopersicum
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.8.3.1 sulfite + O2 + H2O
-
 Solanum lycopersicum sulfate + H2O2
-
 ?

Cofactor

EC Number Cofactor Comment Organism Structure
1.8.3.1 molybdenum cofactor
-
 Solanum lycopersicum

General Information

EC Number General Information Comment Organism
1.8.3.1 malfunction the imbalanced sulfite level resulting from sulfite oxidase impairment confers a metabolic shift towards elevated reduced S-compounds, namely sulfide, S-amino acids (S-AA), Co-A and acetyl-CoA, followed by non-S-AA, nitrogen and carbon metabolite enhancement, including polar lipids. Exposing mutant plants to dark-induced carbon starvation result in a higher degradation of S-compounds, total AA, carbohydrates, polar lipids and total RNA in the mutant plants. Significantly, a failure to balance the carbon backbones is evident in the mutants, indicated by an increase in tricarboxylic acid cycle (TCA) cycle intermediates, whereas a decrease is shown in stressed wild-type plants. Sulfite oxidase deficiency is not necessarily lethal, unless other sulfite network enzymes are down-regulated or the capacity of the sulfite network enzymes in sulfite detoxification is exceeded. Sulfite oxidase mutation affects carbon metabolism in normal and dark-stressed plants. Extended dark stress leads to enhanced degradation of organic nitrogen, elevated ammonium and preference for lower C/N ratio metabolites in the sulfite oxidase mutants as compared with the wild-type plants. Phenotype, detailed overview Solanum lycopersicum
1.8.3.1 physiological function sulfite oxidase activity is essential for normal sulfur, nitrogen and carbon metabolism in tomato leaves. The enzyme is a key player in protecting plants against exogenous toxic sulfite. And the enzyme activity is essential to cope with rising dark-induced endogenous sulfite levels in tomato plants. The role of sulfite oxidase is not limited to a rescue reaction under elevated sulfite, but sulfite oxidase is a key player in maintaining optimal carbon, nitrogen and sulfur metabolism in tomato plants Solanum lycopersicum