EC Number | Cloned (Comment) | Organism |
---|---|---|
1.14.11.67 | gene SE14, map-based cloning of Se14, DNA and amino acid sequence determination and analysis, sequence comparisons, fine mapping of the Se14 locus on the short arm of chromosome 3, genetic interaction of the Se14 locus with other flowering time genes loci and gene expression analysis | Oryza sativa Japonica Group |
EC Number | Protein Variants | Comment | Organism |
---|---|---|---|
1.14.11.67 | additional information | generation of Se14-deficient mutant line HS112, an early flowering time mutant, Diurnal expression of flowering time genes in the wild-type and HS112, overview | Oryza sativa Japonica Group |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
1.14.11.67 | chromatin | - |
Oryza sativa Japonica Group | 785 | - |
1.14.11.67 | nucleus | - |
Oryza sativa Japonica Group | 5634 | - |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.14.11.67 | histone H3 N6,N6,N6-trimethyl-L-lysine4 + 2-oxoglutarate + O2 | Oryza sativa Japonica Group | SE14 catalyzes H3K4me3 demethylation in the promoter region of RFT1 | histone H3 N6,N6-dimethyl-L-lysine4 + succinate + formaldehyde + CO2 | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.14.11.67 | Oryza sativa Japonica Group | Q10RP4 | - |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.14.11.67 | histone H3 N6,N6,N6-trimethyl-L-lysine4 + 2-oxoglutarate + O2 | - |
Oryza sativa Japonica Group | histone H3 N6,N6-dimethyl-L-lysine4 + succinate + formaldehyde + CO2 | - |
? | |
1.14.11.67 | histone H3 N6,N6,N6-trimethyl-L-lysine4 + 2-oxoglutarate + O2 | SE14 catalyzes H3K4me3 demethylation in the promoter region of RFT1 | Oryza sativa Japonica Group | histone H3 N6,N6-dimethyl-L-lysine4 + succinate + formaldehyde + CO2 | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.14.11.67 | Lysine-specific demethylase SE14 | UniProt | Oryza sativa Japonica Group |
1.14.11.67 | Os03g0151300 | locus name | Oryza sativa Japonica Group |
1.14.11.67 | SE14 | - |
Oryza sativa Japonica Group |
EC Number | General Information | Comment | Organism |
---|---|---|---|
1.14.11.67 | evolution | the SE14 enzyme is Jumonji C (JmjC) domain-containing protein, overview | Oryza sativa Japonica Group |
1.14.11.67 | malfunction | Se14-deficient mutant line HS112 is an early flowering time mutant. The expressions of RFT1, a floral initiator known as a florigen-like gene, and Ehd1, a flowering time activator, are upregulated in Se14-deficient mutant line HS112, whereas this upregulation is not observed in the original variety of Gimbozu. The trimethylated H3K4 in the promoter region of the RFT1 chromatin is significantly increased in mutant line HS112 | Oryza sativa Japonica Group |
1.14.11.67 | physiological function | Se14 is a photoperiod-sensitivity gene that has a suppressive effect on floral transition (flowering time) under long day-length conditions through the modification of chromatin structure by H3K4me3 demethylation in the promoter region of RFT1 | Oryza sativa Japonica Group |