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Literature summary extracted from
- Indole alkaloids from tropical sponge Hyrtios sp. as isocitrate lyase inhibitors (2018), Nat. Prod. Commun., 13, 683-685 .
No PubMed abstract available
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 4.1.3.1 | 3,4-dihydrohyrtiosulawesine | - |
Candida albicans |  |
| 4.1.3.1 | beta-ketoserotonin | - |
Candida albicans | |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 4.1.3.1 | isocitrate | Candida albicans | - |
succinate + glyoxylate | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 4.1.3.1 | Candida albicans | - |
- |
- |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 4.1.3.1 | isocitrate | - |
Candida albicans | succinate + glyoxylate | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 4.1.3.1 | ICL | - |
Candida albicans |
IC50 Value
| EC Number | IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
|---|---|---|---|---|---|---|
| 4.1.3.1 | 0.0929 | - |
pH and temperature not specified in the publication | Candida albicans | 3,4-dihydrohyrtiosulawesine | |
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Release 2023.1 (January 2023)
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