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Literature summary extracted from

  • Aschenbrenner, A.K.; Kwon, M.; Conrad, J.; Ro, D.K.; Spring, O.
    Identification and characterization of two bisabolene synthases from linear glandular trichomes of sunflower (Helianthus annuus L., Asteraceae) (2016), Phytochemistry, 124, 29-37 .
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
4.2.3.40 gene TPS12_K7, cloning of two isozymes of bisabolene synthases from RNA, DNA and amino acid sequence determination and analysis, the sequences contain the typical motifs of sesquiterpene synthases, sequence comparisons, functional recombinant expression in yeast Helianthus annuus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.2.3.40 (2E,6E)-farnesyl diphosphate Helianthus annuus
-
 (Z)-gamma-bisabolene + diphosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
4.2.3.40 Helianthus annuus A0A125S8N1
-
-
4.2.3.40 Helianthus annuus A0A125S8N2
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
4.2.3.40 trichome identification of two bisabolene synthases from linear glandular trichomes of sunflower that produce (Z)gamma-bisabolene Helianthus annuus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.2.3.40 (2E,6E)-farnesyl diphosphate
-
 Helianthus annuus (Z)-gamma-bisabolene + diphosphate
-
 ?
4.2.3.40 additional information NMR spectroscopy product analysis Helianthus annuus ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
4.2.3.40 (Z)-gamma-bisabolene synthase K11
-
 Helianthus annuus
4.2.3.40 (Z)-gamma-bisabolene synthase K7
-
 Helianthus annuus
4.2.3.40 TPS12_K7
-
 Helianthus annuus

General Information

EC Number General Information Comment Organism
4.2.3.40 physiological function the initial step in the biosynthesis of a variety of bisabolene-type sesquiterpenes, that accumulate in trichomes of leaves, stems and flowering parts, from its precursor farnesyl diphosphate is catalyzed by two bisabolene synthases identified in the RNA pool of linear glandular trichomes of sunflower Helianthus annuus