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Literature summary extracted from

  • Kadokura, H.; Beckwith, J.
    Four cysteines of the membrane protein DsbB act in concert to oxidize its substrate DsbA (2002), EMBO J., 21, 2354-2363 .
    View publication on PubMedView publication on EuropePMC

Protein Variants

EC Number Protein Variants Comment Organism
1.8.5.9 R48H the mutant shows reduced activity compared to the wild type enzyme Escherichia coli

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.8.5.9 cytoplasmic membrane
-
 Escherichia coli
-
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.8.5.9 a [DsbA protein] with reduced L-cysteine residues + a quinone Escherichia coli overall reaction a [DsbA protein] carrying a disulfide bond + a quinol
-
 ?
1.8.5.9 a [DsbA protein] with reduced L-cysteine residues + a [DsbB protein] carrying a disulfide bond Escherichia coli
-
 a [DsbA protein] carrying a disulfide bond + a [DsbB protein] with reduced L-cysteine residues
-
 ?
1.8.5.9 a [DsbB protein] with reduced L-cysteine residues + a quinone Escherichia coli
-
 a [DsbB protein] carrying a disulfide bond + a quinol
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.8.5.9 Escherichia coli
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.8.5.9 a [DsbA protein] with reduced L-cysteine residues + a quinone overall reaction Escherichia coli a [DsbA protein] carrying a disulfide bond + a quinol
-
 ?
1.8.5.9 a [DsbA protein] with reduced L-cysteine residues + a [DsbB protein] carrying a disulfide bond
-
 Escherichia coli a [DsbA protein] carrying a disulfide bond + a [DsbB protein] with reduced L-cysteine residues
-
 ?
1.8.5.9 a [DsbB protein] with reduced L-cysteine residues + a quinone
-
 Escherichia coli a [DsbB protein] carrying a disulfide bond + a quinol
-
 ?
1.8.5.9 additional information the enzyme uses its two pairs of cysteines in a coordinated reaction to accept electrons from the active cysteines in DsbA protein Escherichia coli ?
-
-

Synonyms

EC Number Synonyms Comment Organism
1.8.5.9 DsbB
-
 Escherichia coli