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Literature summary extracted from

  • Dey, S.; Ray, K.
    Cholinergic activity is essential for maintaining the anterograde transport of choline acetyltransferase in Drosophila (2018), Sci. Rep., 8, 8028 .
    View publication on PubMedView publication on EuropePMC

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.6 Drosophila melanogaster P07668
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Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.6 neuron sensory neuron Drosophila melanogaster
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General Information

EC Number General Information Comment Organism
2.3.1.6 physiological function direct interaction between the kinesin-2 motor and ChAT for brief duration induces the episodic flow towards synapse, and synaptic activity is essential for this interaction. Blocking the acetylcholine synthesis through the HC3 treatment, and activation of the post synaptic neurons through the inhibition of actylcholine receptors by BTX, respectively, reduce the axonal entry and disrupt the episodic nature of ChAT transport within a short time Drosophila melanogaster