EC Number | Cloned (Comment) | Organism |
---|---|---|
1.1.1.42 | expressed in Escherichia coli DH5alpha cells | Sus scrofa |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
1.1.1.42 | cytosol | - |
Sus scrofa | 5829 | - |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
1.1.1.42 | Mn2+ | 1 mM used in assay conditions | Sus scrofa |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.1.1.42 | isocitrate + NADP+ | Sus scrofa | - |
2-oxoglutarate + CO2 + NADPH + H+ | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.1.1.42 | Sus scrofa | A0A4X1UZU9 | - |
- |
EC Number | Posttranslational Modification | Comment | Organism |
---|---|---|---|
1.1.1.42 | phosphoprotein | tyrosine phosphorylated enzyme shows a significantly lowered enzymatic activity | Sus scrofa |
EC Number | Purification (Comment) | Organism |
---|---|---|
1.1.1.42 | glutathione-Sepharose column chromatography and DEAE-Sepharose chromatography | Sus scrofa |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
1.1.1.42 | semen | mainly localized to the principal piece of the porcine sperm flagellum | Sus scrofa | - |
1.1.1.42 | testis | - |
Sus scrofa | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.1.1.42 | isocitrate + NADP+ | - |
Sus scrofa | 2-oxoglutarate + CO2 + NADPH + H+ | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
1.1.1.42 | ? | x * 45000, SDS-PAGE | Sus scrofa |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.1.1.42 | IDPc | - |
Sus scrofa |
1.1.1.42 | NADP+-dependent isocitrate dehydrogenase | - |
Sus scrofa |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
1.1.1.42 | NADP+ | - |
Sus scrofa |
EC Number | Organism | Comment | Expression |
---|---|---|---|
1.1.1.42 | Sus scrofa | enzyme activities decrease following capacitation of sperm | down |