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Literature summary extracted from

  • Kim, S.H.; Khan, R.; Choi, K.; Lee, S.W.; Rhee, S.
    A triclosan-resistance protein from the soil metagenome is a novel enoyl-acyl carrier protein reductase Structure-guided functional analysis (2020), FEBS J., 287, 4710-4728 .
    View publication on PubMed

Protein Variants

EC Number Protein Variants Comment Organism
1.3.1.9 K266A strain carrying the mutation is not viable at nonpermissive temperature. 1% of wild-type activity uncultured bacterium
1.3.1.9 Y260F strain carrying the mutation is not viable at nonpermissive temperature. 5.7% of wild-type activity uncultured bacterium

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.3.1.9 0.043
-
 NADH pH 5.5, 30°C uncultured bacterium
1.3.1.9 1.26
-
 crotonoyl-CoA pH 5.5, 30°C uncultured bacterium

Organism

EC Number Organism UniProt Comment Textmining
1.3.1.9 uncultured bacterium A0A1C9HA64
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.3.1.9 crotonoyl-CoA + NADH + H+
-
 uncultured bacterium butanoyl-CoA + NAD+
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.3.1.9 FabMG
-
 uncultured bacterium

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
1.3.1.9 38
-
 NADH pH 5.5, 30°C uncultured bacterium
1.3.1.9 100
-
 crotonoyl-CoA pH 5.5, 30°C uncultured bacterium

Cofactor

EC Number Cofactor Comment Organism Structure
1.3.1.9 NADH
-
 uncultured bacterium