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Literature summary extracted from
- The di-heme family of respiratory complex II enzymes (2013), Biochim. Biophys. Acta, 1827, 679-687 .
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 7.1.1.12 | 2-hydroxy-3-neopentyl-1,4-naphthoquinone | - |
Bacillus licheniformis | |
| 7.1.1.12 | 2-n-heptyl-4-hydroxyquinoline N-oxide | - |
Bacillus subtilis |  |
| 7.1.1.12 | 2-n-heptyl-4-hydroxyquinoline N-oxide | - |
Corynebacterium glutamicum | |
| 7.1.1.12 | 2-n-heptyl-4-hydroxyquinoline N-oxide | - |
Thermoplasma acidophilum | |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 7.1.1.12 | membrane | - |
Bacillus subtilis | 16020 | - |
| 7.1.1.12 | membrane | - |
Thermus thermophilus | 16020 | - |
| 7.1.1.12 | membrane | - |
Thermoplasma acidophilum | 16020 | - |
| 7.1.1.12 | membrane | - |
Corynebacterium glutamicum | 16020 | - |
| 7.1.1.12 | membrane | - |
Bacillus licheniformis | 16020 | - |
| 7.1.1.12 | membrane | - |
Rhodothermus marinus | 16020 | - |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 7.1.1.12 | succinate + menaquinone + 2 H+[side 1] | Bacillus subtilis | the enzyme supports an electron transfer across the biological membranes in which it is embedded. The electrogenic reaction allows the transmembrane electrochemical proton potential DELTAp to drive the endergonic oxidation of succinate by menaquinone | fumarate + menaquinol + 2 H+[side 2] | - |
? | |
| 7.1.1.12 | succinate + menaquinone + 2 H+[side 1] | Thermus thermophilus | the enzyme supports an electron transfer across the biological membranes in which it is embedded. The electrogenic reaction allows the transmembrane electrochemical proton potential DELTAp to drive the endergonic oxidation of succinate by menaquinone | fumarate + menaquinol + 2 H+[side 2] | - |
? | |
| 7.1.1.12 | succinate + menaquinone + 2 H+[side 1] | Thermoplasma acidophilum | the enzyme supports an electron transfer across the biological membranes in which it is embedded. The electrogenic reaction allows the transmembrane electrochemical proton potential DELTAp to drive the endergonic oxidation of succinate by menaquinone | fumarate + menaquinol + 2 H+[side 2] | - |
? | |
| 7.1.1.12 | succinate + menaquinone + 2 H+[side 1] | Corynebacterium glutamicum | the enzyme supports an electron transfer across the biological membranes in which it is embedded. The electrogenic reaction allows the transmembrane electrochemical proton potential DELTAp to drive the endergonic oxidation of succinate by menaquinone | fumarate + menaquinol + 2 H+[side 2] | - |
? | |
| 7.1.1.12 | succinate + menaquinone + 2 H+[side 1] | Bacillus licheniformis | the enzyme supports an electron transfer across the biological membranes in which it is embedded. The electrogenic reaction allows the transmembrane electrochemical proton potential DELTAp to drive the endergonic oxidation of succinate by menaquinone | fumarate + menaquinol + 2 H+[side 2] | - |
? | |
| 7.1.1.12 | succinate + menaquinone + 2 H+[side 1] | Rhodothermus marinus | the enzyme supports an electron transfer across the biological membranes in which it is embedded. The electrogenic reaction allows the transmembrane electrochemical proton potential DELTAp to drive the endergonic oxidation of succinate by menaquinone | fumarate + menaquinol + 2 H+[side 2] | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 7.1.1.12 | Bacillus licheniformis | - |
- |
- |
| 7.1.1.12 | Bacillus subtilis | - |
- |
- |
| 7.1.1.12 | Corynebacterium glutamicum | - |
- |
- |
| 7.1.1.12 | Rhodothermus marinus | - |
- |
- |
| 7.1.1.12 | Thermoplasma acidophilum | - |
- |
- |
| 7.1.1.12 | Thermus thermophilus | - |
- |
- |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 7.1.1.12 | succinate + menaquinone + 2 H+[side 1] | the enzyme supports an electron transfer across the biological membranes in which it is embedded. The electrogenic reaction allows the transmembrane electrochemical proton potential DELTAp to drive the endergonic oxidation of succinate by menaquinone | Bacillus subtilis | fumarate + menaquinol + 2 H+[side 2] | - |
? | |
| 7.1.1.12 | succinate + menaquinone + 2 H+[side 1] | the enzyme supports an electron transfer across the biological membranes in which it is embedded. The electrogenic reaction allows the transmembrane electrochemical proton potential DELTAp to drive the endergonic oxidation of succinate by menaquinone | Thermus thermophilus | fumarate + menaquinol + 2 H+[side 2] | - |
? | |
| 7.1.1.12 | succinate + menaquinone + 2 H+[side 1] | the enzyme supports an electron transfer across the biological membranes in which it is embedded. The electrogenic reaction allows the transmembrane electrochemical proton potential DELTAp to drive the endergonic oxidation of succinate by menaquinone | Thermoplasma acidophilum | fumarate + menaquinol + 2 H+[side 2] | - |
? | |
| 7.1.1.12 | succinate + menaquinone + 2 H+[side 1] | the enzyme supports an electron transfer across the biological membranes in which it is embedded. The electrogenic reaction allows the transmembrane electrochemical proton potential DELTAp to drive the endergonic oxidation of succinate by menaquinone | Corynebacterium glutamicum | fumarate + menaquinol + 2 H+[side 2] | - |
? | |
| 7.1.1.12 | succinate + menaquinone + 2 H+[side 1] | the enzyme supports an electron transfer across the biological membranes in which it is embedded. The electrogenic reaction allows the transmembrane electrochemical proton potential DELTAp to drive the endergonic oxidation of succinate by menaquinone | Bacillus licheniformis | fumarate + menaquinol + 2 H+[side 2] | - |
? | |
| 7.1.1.12 | succinate + menaquinone + 2 H+[side 1] | the enzyme supports an electron transfer across the biological membranes in which it is embedded. The electrogenic reaction allows the transmembrane electrochemical proton potential DELTAp to drive the endergonic oxidation of succinate by menaquinone | Rhodothermus marinus | fumarate + menaquinol + 2 H+[side 2] | - |
? | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 7.1.1.12 | oligomer | x * 63000 + x * 27000 + x * 15000 + x * 14000 | Thermoplasma acidophilum |
| 7.1.1.12 | oligomer | x * 64000 + x * 27000 + x * 15000 + x * 14000 | Thermus thermophilus |
| 7.1.1.12 | oligomer | x * 65000 + x * 28000 + x * 23000 | Bacillus subtilis |
| 7.1.1.12 | oligomer | x * 65000 + x * 28000 + x * 23000 | Bacillus licheniformis |
| 7.1.1.12 | oligomer | x * 70000 + x * 32000 + x * 18000 | Rhodothermus marinus |
| 7.1.1.12 | oligomer | x * 75000 + x * 28000 + x * 27000 | Corynebacterium glutamicum |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 7.1.1.12 | SQR | - |
Bacillus subtilis |
| 7.1.1.12 | SQR | - |
Thermus thermophilus |
| 7.1.1.12 | SQR | - |
Thermoplasma acidophilum |
| 7.1.1.12 | SQR | - |
Corynebacterium glutamicum |
| 7.1.1.12 | SQR | - |
Bacillus licheniformis |
| 7.1.1.12 | SQR | - |
Rhodothermus marinus |
| 7.1.1.12 | succinate:quinone oxidoreductases | - |
Bacillus subtilis |
| 7.1.1.12 | succinate:quinone oxidoreductases | - |
Thermus thermophilus |
| 7.1.1.12 | succinate:quinone oxidoreductases | - |
Thermoplasma acidophilum |
| 7.1.1.12 | succinate:quinone oxidoreductases | - |
Corynebacterium glutamicum |
| 7.1.1.12 | succinate:quinone oxidoreductases | - |
Bacillus licheniformis |
| 7.1.1.12 | succinate:quinone oxidoreductases | - |
Rhodothermus marinus |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 7.1.1.12 | heme | contains two heme molecules | Bacillus subtilis | |
| 7.1.1.12 | heme | contains two heme molecules | Thermus thermophilus | |
| 7.1.1.12 | heme | contains two heme molecules | Thermoplasma acidophilum | |
| 7.1.1.12 | heme | contains two heme molecules | Corynebacterium glutamicum | |
| 7.1.1.12 | heme | contains two heme molecules | Bacillus licheniformis | |
| 7.1.1.12 | heme | contains two heme molecules | Rhodothermus marinus | |
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