Literature summary extracted from

Darville, M.I.; Crepin, K.M.; Vandekerckhove, J.; Van Damme, J.; Octave, J.N.; Rider, MH.; Marchand, M.J.; Hue, L.; Rousseau, G.G.
Complete nucleotide sequence coding for rat liver 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase derived from a cDNA clone (1987), FEBS Lett., 224, 317-321.

Cloned(Commentary)

EC Number	Cloned (Comment)	Organism
3.1.3.46	-	Rattus norvegicus

Localization

EC Number	Localization	Comment	Organism	GeneOntology No.	Textmining
3.1.3.46	cytosol	-	Rattus norvegicus	5829	-

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
3.1.3.46	fructose 2,6-bisphosphate + H2O	Rattus norvegicus	-	?	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
3.1.3.46	Rattus norvegicus	P07953	-	-

Reaction

EC Number	Reaction	Comment	Organism	Reaction ID
3.1.3.46	beta-D-fructose 2,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate	bifunctional enzyme: 6-phosphofructo-2-kinase-fructose-2,6-bisphosphatase	Rattus norvegicus	a

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
3.1.3.46	liver	-	Rattus norvegicus	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
3.1.3.46	fructose 2,6-bisphosphate + H2O	-	Rattus norvegicus	fructose 6-phosphate + phosphate	-	?
3.1.3.46	fructose 2,6-bisphosphate + H2O	-	Rattus norvegicus	?	-	?

Subunits

EC Number	Subunits	Comment	Organism
3.1.3.46	dimer	2 * 50000-55000, SDS-PAGE	Rattus norvegicus

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Release 2023.1 (January 2023)