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Gene ontology
Version 2014-12-22
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Details for 15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity
1.1.1.196
Gene ontology ID
GO:0047020
Definition
Catalysis of the reaction: NADP+ + (5Z,13E)-(15S)-9-alpha,15-dihydroxy-11-oxoprosta-5,13-dienoate = NADPH + H+ + (5Z,13E)-9-alpha-hydroxy-11,15-dioxoprosta-5,13-dienoate
Synonyms
1. (5Z,13E)-(15S)-9alpha,15-dihydroxy-11-oxoprosta-5,13-dienoate:NADP+ 15-oxidoreductase activity
2. 15-hydroxy PGD2 dehydrogenase activity
3. 15-hydroxyprostaglandin dehydrogenase (NADP)
4. dehydrogenase, 15-hydroxyprostaglandin (nicotinamide adenine dinucleotide phosphate)
5. dehydrogenase, prostaglandin D2
6. NADP-dependent 15-hydroxyprostaglandin dehydrogenase
7. NADP-linked 15-hydroxyprostaglandin dehydrogenase
8. NADP-linked prostaglandin D2 dehydrogenase activity
9. NADP-PGD2 dehydrogenase activity
10. NADP-specific 15-hydroxyprostaglandin dehydrogenase
11. prostaglandin D2 dehydrogenase activity
12. prostaglandin-D 15-dehydrogenase (NADP(+)) activity
13. prostaglandin-D 15-dehydrogenase (NADP)
14. prostaglandin-D 15-dehydrogenase (NADP+) activity
References
1. EC 1.1.1.196
2. MetaCyc 1.1.1.196-RXN
3. RHEA: 20744
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