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Version 2014-12-22
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Details for S-(hydroxymethyl)glutathione dehydrogenase activity
1.1.1.284
Gene ontology ID
GO:0051903
Definition
Catalysis of the reaction: S-(hydroxymethyl)glutathione + NAD(P)+ = S-formylglutathione + NAD(P)H + H+
Synonyms
1. ADH3 activity
2. chi-ADH activity
3. class III alcohol dehydrogenase activity
4. FDH activity
5. formic dehydrogenase activity
6. GD-FALDH activity
7. glutathione-dependent formaldehyde dehydrogenase activity
8. GS-FDH activity
9. NAD- and glutathione-dependent formaldehyde dehydrogenase activity
10. NAD-dependent formaldehyde dehydrogenase activity
11. NAD-linked formaldehyde dehydrogenase activity
12. S-(hydroxymethyl)glutathione:NAD+ oxidoreductase activity
References
1. EC 1.1.1.284
2. KEGG REACTION: R06983
3. KEGG REACTION: R07140
4. MetaCyc RXN-2962
5. Reactome: R-HSA-5692237 "ADH5 oxidises S-HMGSH to S-FGSH"
6. RHEA: 19981
7. RHEA: 19985
8. UM-BBD reactionID: r1146
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