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Gene ontology
Version 2014-12-22
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Details for deoxyhypusine monooxygenase activity
1.14.99.29
Gene ontology ID
GO:0019135
Definition
Catalysis of the reaction: protein N6-(4-aminobutyl)-L-lysine + donor-H2 + O2 = protein N6-((R)-4-amino-2-hydroxybutyl)-L-lysine + acceptor + H2O
Synonyms
1. deoxyhypusine dioxygenase activity
2. deoxyhypusine hydroxylase activity
3. deoxyhypusine,hydrogen-donor:oxygen oxidoreductase (2-hydroxylating)
4. DOHH activity
References
1. EC 1.14.99.29
2. MetaCyc DEOXYHYPUSINE-MONOOXYGENASE-RXN
3. Reactome: R-HSA-204662 "DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A"
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