6.3.4.4 AMP ASS expression is induced by AMP 6.3.4.4 D-fructose 1,6 bisphosphate binds to the Asp loop and induces a conformation that facilitates aspartate binding to the enzyme active site 6.3.4.4 D-fructose 1,6-diphosphate activates 6.3.4.4 NH4+ ASS expression is induced rather than repressed by NH4