1.3.1.70 detergents such as Lubrol-WX, Emulgen 911, Triton X-100, Triton WR-1339, and their combinations with ionic detergents such as taurodeoxycholate, cholate, and Na+ salts destroy enzyme even at low concentration, 0.1-0.5%, w/v 288490 1.3.1.70 enzyme in soluble form is very instable 288490 1.3.1.70 enzyme very labile 288489, 288491 1.3.1.70 stable against trypsin treatment 288490 1.3.1.70 The enzyme is degraded by the proteasome and ubiquitinated. Enzyme turnover is triggered by a wide variety of sterols 765069 1.3.1.70 very labile membrane-bound enzyme, totally dependent on the presence of liposome and NADPH 288491