1.1.1.76 2-mercaptoethanol competitive inhibition; competitive inhibitor 63 1.1.1.76 2-mercaptoethanol competitive. In crystal structure, the mercaptoethanol molecule is located in the catalytic cleft formed by residues Ser141, Ileu142, Ala143, Phe148, Tyr154, Pro184, Gly185, Ileu186, Met191, Trp192 and Ile195. These residues may also be involved in substrate recognition and in stereospecific redox reactions 63 1.1.1.76 acetate slight inhibition at 5 mM 47 1.1.1.76 Ag+ strong inhibition 75 1.1.1.76 Al3+ strong inhibition 264 1.1.1.76 Cu2+ 5 mM, 89% inhibition; 89% inhibition at 5 mM 19 1.1.1.76 Cu2+ strong inhibition 19 1.1.1.76 Fe3+ strong inhibition 70 1.1.1.76 formate slight inhibition at 5 mM 120 1.1.1.76 Hg2+ 100% inhibition at 5 mM; 5 mM, 100% inhibition 33 1.1.1.76 K+ slight inhibition 39 1.1.1.76 Lactate slight inhibition at 5 mM 1219 1.1.1.76 additional information slight inhibition of 10-20% by organic acids at concentrations of 5 mM: lactate, pyruvate, succinate, acetate and formate 2 1.1.1.76 additional information not inhibited by EDTA 2 1.1.1.76 pyruvate slight inhibition at 5 mM 31 1.1.1.76 succinate slight inhibition at 5 mM 58 1.1.1.76 Zn2+ slight inhibition 14