1.17.4.4 chloroplast - 9507 745995 1.17.4.4 endoplasmic reticulum - 5783 701401 1.17.4.4 endoplasmic reticulum ER membrane localisation, the enzyme has a typical ER retention signal, KAKRH at the C-terminus of the protein which is indispensable to activity 5783 746471 1.17.4.4 endoplasmic reticulum integral membrane enzyme of the endoplasmic reticulum 5783 744342 1.17.4.4 endoplasmic reticulum integral protein 5783 657400 1.17.4.4 endoplasmic reticulum topology with large loop between transmembrane one and two facing the lumen of the endoplasmic reticulum (ER). A redox sensitive green fluorescent protein is fused to the N- or C-terminus to show that these regions face the cytosol, and introduction of glycosylation sites along with mixed disulfide formation with thioredoxin-like transmembrane protein (TMX) demonstrate ER localization of the major loop 5783 744273 1.17.4.4 endoplasmic reticulum transmembrane protein 5783 656865 1.17.4.4 endoplasmic reticulum membrane - 5789 674854, 716060 1.17.4.4 endoplasmic reticulum membrane integral membrane protein, topology, overview 5789 724800 1.17.4.4 endoplasmic reticulum membrane membrane topology, overview 5789 671387