3.4.24.28	Ca2+	100 mM, 60% activation	667347	
3.4.24.28	Ca2+	30% activation at 10 mM	717233	
3.4.24.28	Ca2+	5 mM Ca2+ stabilizes the enzyme	711482	
3.4.24.28	Ca2+	activates 20% at 10 mM	733130	
3.4.24.28	Calcium	2 calcium binding sites	31154	
3.4.24.28	Co2+	30% activation at 8 mM, 40% inhibition at 10 mM	733167	
3.4.24.28	Li+	activates 20% at 10 mM	733130	
3.4.24.28	Mg2+	20% activation at 10 mM	717233	
3.4.24.28	Mg2+	activates 20% at 10 mM	733130	
3.4.24.28	Mn2+	activates 2.90fold at 10 mM	733130	
3.4.24.28	additional information	metalloprotease	733469	
3.4.24.28	additional information	no effect by Ca2+	733167	
3.4.24.28	Zinc	zinc enzyme	31112, 31157, 31159, 31162	
3.4.24.28	Zn2+	a zinc metalloprotease	733130	
3.4.24.28	Zn2+	required, exogenous Zn2+ activates at 1 mM	733167	
3.4.24.28	Zn2+	secreted zinc-dependent endopeptidase, addition of exogenous Zn2+ at 0.01 mM inhibits the enzyme	717233	
3.4.24.28	Zn2+	Zn2+ ions, although essential cofactors and exhibiting extremely high affinity, are without effect on the stability	711482