1.21.3.6 copper two copper atoms, CuA and CuB, are located in the active site and each is coordinated by three histidine residues. CuA is coordinated by His87, His108, and His117 residues, while CuB is coordinated by His241, His245 and His275 727629 1.21.3.6 Cu2+ a copper-containing enzyme 744988 1.21.3.6 Cu2+ copper-containing enzyme, bound via histidine residues in the active site 644709