1.12.98.3 H2 + 2-(2,3-dihydropentaprenyloxy)phenazine - 1.12.98.3 H2 + 2-(2,3-dihydropentaprenyloxy)phenazine enzyme is part of a membrane-bound electron transport system in methanogenesis 1.12.98.3 H2 + 2-(2,3-dihydropentaprenyloxy)phenazine coenzyme F420-dependent reduction of 2-hydroxyphenazine as catalyzed by the membrane-bound enzyme is coupled to proton translocation across the cytoplasmic membrane, exhibiting a stoichiometry of 0.9 H+ translocated per two electrons transferred. The electrochemical proton gradient thereby generated drives ATP synthesis from ADP and diphosphate