1.14.14.115 oleanolic acid + [reduced NADPH-hemoprotein reductase] + O2 hydroxylation at C-16beta 1.14.14.115 beta-amyrin + [reduced NADPH-hemoprotein reductase] + O2 hydroxylation at C-16beta, main activity of enzyme CYP716A141 1.14.14.115 maniladiol + [reduced NADPH-hemoprotein reductase] + O2 hydroxylation at C-28 1.14.14.115 beta-amyrin + [reduced NADPH-hemoprotein reductase] + O2 hydroxylation at C-28, reaction of EC 1.14.13.201 1.14.14.115 11-oxo-beta-amyrin + O2 + [reduced NADPH-hemoprotein reductase] the enzyme mainly catalyzes the C-30 hydroxylation of 11-oxo-beta-amyrin to yield 30-hydroxy-11-oxo-beta-amyrin as the major product, accompanied by its isomers as minor products