1.14.14.98	additional information	the enzyme is specifically present in different plant species that produce benzo[c]phenanthridine alkaloids in culture	
1.14.14.98	protopine + [reduced NADPH-hemoprotein reductase] + O2	hydroxylation of protopine by protopine 6-hydroxylase produces the unstable intermediate 6-hydroxyprotopine that spontaneously rearranges to form dihydrosanguinarine