1.5.3.10 additional information bifunctional enzyme catalyzing the formation of 5,10-methylene tetrahydrofolate and the oxidation of N,N-dimethylglycine, folate binding and active site, a large channel connects both active sites, the channeling is kinetically controlled by terahydrofolate binding, overview 1.5.3.10 N,N-dimethylglycine + H2O + O2 - 1.5.3.10 N,N-dimethylglycine + H2O + O2 involved in tetrahydrofolate-dependent assimilation of methyl groups