1.8.3.1	additional information	the enzyme is believed to detoxify excess sulfite that is produced during sulfur assimilation, or due to air pollution	
1.8.3.1	sulfite + cytochrome c	detoxification	
1.8.3.1	sulfite + cytochrome c	genetic deficiency results in neurological abnormities	
1.8.3.1	sulfite + cytochrome c	catalytic cycle	
1.8.3.1	sulfite + cytochrome c	natural acceptor	
1.8.3.1	sulfite + O2 + H2O	-	
1.8.3.1	sulfite + O2 + H2O	lack of active enzyme produces severe neurodegeneration and early death in humans	
1.8.3.1	sulfite + O2 + H2O	sulfite is the physiological substrate	
1.8.3.1	sulfite + O2 + H2O	the enzyme catalyzes the oxidation of sulfite to sulfate using ferricytochrome c as the physiological electron acceptor	
1.8.3.1	sulfite + O2 + H2O	under normal physiological conditions, SO catalyzes the oxidation of sulfite to sulfate with cytochrome c (cyt c) as oxidizing substrate