3.2.1.31 beta-glucuronidase toxicology in environmental toxicology, techniques used to visualise lysosomes in order to determine their responses to pollutants are the lysosomal structural changes test and the lysosomal membrane stability test are based on the histochemical application of lysosomal marker enzymes. In mussel digestive cells, the marker enzymes used are beta-glucuronidase and hexosaminidase. beta-Glucuronidase, but not hexosaminindase, histochemistry provides an appropriate marker for the lysosomal structural changes test and that, although both lysosomal marker enzymes can be employed in the lysosomal membrane stability test, different values would be obtained depending on the marker enzyme employed 3.2.1.31 beta-glucuronidase toxicology measurement of beta-glucuronidase activity has no additive clinical value following a parathion overdose in humans