1.1.1.379 synthesis D-mandelate dehydrogenase (DMDH) has the potential to convert D-mandelic acid to phenylglyoxylic acid (PGA), which is a key building block in the field of chemical synthesis and is widely used to synthesize pharmaceutical intermediates or food additives. Development of an alternative strategy for the chiral resolution of racemic mandelic acid and the biosynthesis of PGA 763170