1.1.99.28 D-glucose + D-fructose = D-gluconolactone + D-glucitol mechanism 10904 1.1.99.28 D-glucose + D-fructose = D-gluconolactone + D-glucitol ping-pong mechanism with a single site for all substrates, two half-reactions with alternate reduction of NADP+ and oxidation of NADPH 10902