2.8.3.5 762068 3-Oxoacid CoA transferase 1 as a therapeutic target gene for cisplatin-resistant ovarian cancer Oncol. Lett. 15 2611-2618 2018 Homo sapiens http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29434981&form=6&db=m 2.8.3.5 645968 A simple purification of acetoacetate-succinate CoA-transferase using substrate elution chromatography FEBS Lett. 37 155-158 1973 Sus scrofa http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4763316&form=6&db=m 2.8.3.5 738807 A structural mapping of mutations causing succinyl-CoA:3-ketoacid CoA transferase (SCOT) deficiency J. Inherit. Metab. Dis. 36 983-987 2013 Homo sapiens http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23420214&form=6&db=m 2.8.3.5 645976 Activity of 3-oxo acid CoA-transferase, D-3-hydroxybutyrate dehydrogenase, hexokinase and carnitine palmitoyltransferase in the stomach and small and large intestine of the rat Biochem. J. 200 349-355 1981 Rattus norvegicus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6951579&form=6&db=m 2.8.3.5 724277 Catalytic role of the conformational change in succinyl-CoA:3-oxoacid CoA transferase on binding CoA Biochemistry 49 10319-10328 2010 Sus scrofa http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20977214&form=6&db=m 2.8.3.5 724424 Clinical and molecular characterization of five patients with succinyl-CoA:3-ketoacid CoA transferase (SCOT) deficiency Biochim. Biophys. Acta 1812 619-624 2011 Homo sapiens http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21296660&form=6&db=m 2.8.3.5 645993 Cloning and characterization of a human orthologue of testis-specific succinyl CoA: 3-oxo acid CoA transferase (Scot-t) cDNA Mol. Hum. Reprod. 8 16-23 2002 Homo sapiens http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11756565&form=6&db=m 2.8.3.5 645983 Cloning and characterization of Helicobacter pylori succinyl CoA:acetoacetate CoA-transferase, a novel prokaryotic member of the CoA-transferase family J. Biol. Chem. 272 25659-25667 1997 Helicobacter pylori http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9325289&form=6&db=m 2.8.3.5 645983 Cloning and characterization of Helicobacter pylori succinyl CoA:acetoacetate CoA-transferase, a novel prokaryotic member of the CoA-transferase family J. Biol. Chem. 272 25659-25667 1997 Helicobacter pylori 69A http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9325289&form=6&db=m 2.8.3.5 645967 Coenzyme A transferase. Kinetics and exchange reactions J. Biol. Chem. 242 3468-3480 1967 Sus scrofa - 2.8.3.5 645972 Comparative studies on 3-oxo acid coenzyme A transferase from various rat tissues Biochem. J. 142 619-627 1974 Rattus norvegicus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4464844&form=6&db=m 2.8.3.5 703384 Decreased levels of metabolic enzymes in pancreatic islets of patients with type 2 diabetes Diabetologia 52 1087-1091 2009 Homo sapiens http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19296078&form=6&db=m 2.8.3.5 705523 Detection and characterization of in vivo nitration and oxidation of tryptophan residues in proteins Methods Enzymol. 441 339-349 2008 Rattus norvegicus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18554544&form=6&db=m 2.8.3.5 645994 Diabetes-associated nitration of tyrosine and inactivation of succinyl-CoA:3-oxoacid CoA-transferase Am. J. Physiol. 281 H2289-H2294 2001 Rattus norvegicus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11709394&form=6&db=m 2.8.3.5 661256 Different localization in rat brain of the novel cytosolic ketone body-utilizing enzyme, acetoacetyl-CoA synthetase, as compared to succinyl-CoA:3-oxoacid CoA-transferase Biochim. Biophys. Acta 1729 147-153 2005 Rattus norvegicus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15992942&form=6&db=m 2.8.3.5 645986 dimeric pig heart succinate-coenzyme A transferase zses only one subunit to support catalysis Biochemistry 40 2455-2467 2001 Sus scrofa http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11327867&form=6&db=m 2.8.3.5 703810 Effects of age and calorie restriction on tryptophan nitration, protein content, and activity of succinyl-CoA:3-ketoacid CoA transferase in rat kidney mitochondria Free Radic. Biol. Med. 48 609-618 2009 Rattus norvegicus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20025965&form=6&db=m 2.8.3.5 694193 Identification and characterization of a temperature-sensitive R268H mutation in the human succinyl-CoA:3-ketoacid CoA transferase (SCOT) gene Mol. Genet. Metab. 92 216-221 2007 Homo sapiens http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17706444&form=6&db=m 2.8.3.5 645988 Identification of glutamate 344 as the catalytic residue in the active site of pig heart CoA transferase Protein Sci. 3 975-981 1994 Sus scrofa http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7915164&form=6&db=m 2.8.3.5 672216 Identification of the cysteine residue exposed by the conformational change in pig heart succinyl-CoA:3-ketoacid coenzyme A transferase on binding coenzyme A Biochemistry 46 10852-10863 2007 Sus scrofa http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17718512&form=6&db=m 2.8.3.5 645980 Initial-velocity kinetics of succinoyl-coenzyme A-3-oxo acid coenzyme A-transferase from sheep kidney Biochem. J. 213 179-185 1983 Ovis aries http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6577858&form=6&db=m 2.8.3.5 645985 Isolation and characterization of a haploid germ cell-specific novel complementary deoxyribonucleic acid; testis-specific homologue of succinyl CoA:3-Oxo acid CoA transferase Biol. Reprod. 63 1601-1609 2000 Mus musculus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11090426&form=6&db=m 2.8.3.5 705310 Ketone bodies inhibit the viability of human neuroblastoma cells J. Pediatr. Surg. 44 212-216 2009 Homo sapiens http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19159745&form=6&db=m 2.8.3.5 645974 Ketone body usage by mammals. Acetoacetate substrate inhibition of CoA transferase from various rat tissues Life Sci. 15 811-818 1974 Rattus norvegicus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4549944&form=6&db=m 2.8.3.5 695186 Liver-specific silencing of the human gene encoding succinyl-CoA: 3-ketoacid CoA transferase Tohoku J. Exp. Med. 215 227-236 2008 Homo sapiens http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18648183&form=6&db=m 2.8.3.5 724109 Lower succinyl-CoA:3-ketoacid-CoA transferase (SCOT) and ATP citrate lyase in pancreatic islets of a rat model of type 2 diabetes: knockdown of SCOT inhibits insulin release in rat insulinoma cells Arch. Biochem. Biophys. 499 62-68 2010 Rattus norvegicus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20460097&form=6&db=m 2.8.3.5 737420 Metallothionein prevents diabetes-induced cardiac pathological changes, likely via the inhibition of succinyl-CoA:3-ketoacid coenzyme A transferase-1 nitration at Trp(374) Am. J. Physiol. Endocrinol. Metab. 304 E826-E835 2013 Mus musculus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23423173&form=6&db=m 2.8.3.5 645970 Modification and inactivation of CoA transferase by 2-nitro-5-(thiocyanato)benzoate Biochemistry 20 5183-5187 1981 Sus scrofa http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6945874&form=6&db=m 2.8.3.5 645982 Neonatal hypoglycaemia in severe succinyl-CoA: 3-oxoacid CoA-transferase deficiency J. Inherit. Metab. Dis. 24 587-595 2001 Homo sapiens http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11757586&form=6&db=m 2.8.3.5 676985 New vectors for co-expression of proteins: structure of Bacillus subtilis ScoAB obtained by high-throughput protocols Protein Expr. Purif. 53 396-403 2007 Bacillus subtilis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17363272&form=6&db=m 2.8.3.5 645987 Nitration of succinyl-CoA:3-oxoacid CoA-transferase in rats after endotoxin administration Proc. Natl. Acad. Sci. USA 98 7146-7151 2001 Rattus norvegicus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11416199&form=6&db=m 2.8.3.5 690880 Nitration of tryptophan 372 in succinyl-CoA:3-ketoacid CoA transferase during aging in rat heart mitochondria Biochemistry 46 10130-10144 2007 Rattus norvegicus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17685555&form=6&db=m 2.8.3.5 663018 Patients homozygous for the T435N mutation of succinyl-CoA:3-ketoacid CoA Transferase (SCOT) do not show permanent ketosis Pediatr. Res. 56 858-863 2004 Homo sapiens http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15496607&form=6&db=m 2.8.3.5 660674 Physical training reverses defect in 3-ketoacid CoA-transferase activity in skeletal muscle of diabetic rats Am. J. Physiol. 288 E748-752 2005 Rattus norvegicus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15774485&form=6&db=m 2.8.3.5 645989 Pig heart CoA transferase exists as two oligomeric forms separated by a large kinetic barrier Biochemistry 39 11291-11302 2000 Sus scrofa http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10985774&form=6&db=m 2.8.3.5 645975 Ping-pong chromatography. A novel purification of CoA-transferase Biochem. Biophys. Res. Commun. 62 350-356 1975 Rattus norvegicus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1111526&form=6&db=m 2.8.3.5 645990 Productive interactions between the two domains of pig heart CoA transferase during folding and assembly Biochemistry 36 8807-8820 1997 Sus scrofa http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9220967&form=6&db=m 2.8.3.5 645969 Properties of succinyl-CoA:3-ketoacid coenzyme A transferase J. Biol. Chem. 251 1708-1711 1976 Sus scrofa http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=943396&form=6&db=m 2.8.3.5 645973 Purification and properties of succinyl-CoA:3-oxo-acid CoA-transferase from rat brain J. Neurochem. 38 1446-1452 1982 Rattus norvegicus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6950030&form=6&db=m 2.8.3.5 645979 Purification and properties of succinyl-coenzyme A-3-oxo acid coenzyme A-transferase from sheep kidney Biochem. J. 173 759-765 1978 Ovis aries http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=708372&form=6&db=m 2.8.3.5 645979 Purification and properties of succinyl-coenzyme A-3-oxo acid coenzyme A-transferase from sheep kidney Biochem. J. 173 759-765 1978 Sus scrofa http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=708372&form=6&db=m 2.8.3.5 645995 Role of binding energy with coenzyme A in catalysis by 3-oxoacid coenzyme A transferase Biochemistry 34 11678-11689 1995 Sus scrofa http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7547900&form=6&db=m 2.8.3.5 738997 RpoS and oxidative stress conditions regulate succinyl-CoA: 3-ketoacid-coenzyme A transferase (SCOT) expression in Burkholderia pseudomallei Microbiol. Immunol. 57 605-615 2013 Burkholderia pseudomallei http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23808410&form=6&db=m 2.8.3.5 738997 RpoS and oxidative stress conditions regulate succinyl-CoA: 3-ketoacid-coenzyme A transferase (SCOT) expression in Burkholderia pseudomallei Microbiol. Immunol. 57 605-615 2013 Burkholderia pseudomallei K96243 http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23808410&form=6&db=m 2.8.3.5 645971 Sequence of a cDNA clone encoding pig heart mitochondrial CoA transferase J. Biol. Chem. 267 975-978 1992 Sus scrofa http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1730685&form=6&db=m 2.8.3.5 676034 Single-base substitution at the last nucleotide of exon 6 (c.671G>A), resulting in the skipping of exon 6, and exons 6 and 7 in human succinyl-CoA:3-ketoacid CoA transferase (SCOT) gene Mol. Genet. Metab. 90 291-297 2007 Homo sapiens http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17169596&form=6&db=m 2.8.3.5 737365 Structure of succinyl-CoA:3-ketoacid CoA transferase from Drosophila melanogaster Acta Crystallogr. Sect. F 69 1089-1093 2013 Drosophila melanogaster http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24100554&form=6&db=m 2.8.3.5 660636 Structure of the CoA transferase from pig heart to 1.7 A resolution ACTA CRYSTALLOGR. SECT. D 60 1717-1725 2004 Sus scrofa http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15388917&form=6&db=m 2.8.3.5 645978 Substrate specificity and mechanism of action of acetoacetate coenzyme A transferase from rat heart Biochemistry 13 3884-3889 1974 Rattus norvegicus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4415977&form=6&db=m 2.8.3.5 645984 Succinyl CoA:3-oxoacid CoA transferase (SCOT): human cDNA cloning, human chromosomal mapping to 5p13, and mutation detection in a SCOT-deficient patient Am. J. Hum. Genet. 59 519-528 1996 Homo sapiens http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8751852&form=6&db=m 2.8.3.5 645992 Succinyl-CoA:3-ketoacid CoA transferase (SCOT) deficiency: two pathogenic mutations, V133E and C456F, in Japanese siblings Hum. Mutat. 12 83-88 1998 Homo sapiens http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9671268&form=6&db=m 2.8.3.5 645991 Succinyl-CoA:3-ketoacid coenzyme A transferase (SCOT): development of an antibody to human SCOT and diagnostic use in hereditary SCOT deficiency Biochim. Biophys. Acta 1360 151-156 1997 Homo sapiens http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9128180&form=6&db=m 2.8.3.5 723826 The high-resolution structure of pig heart succinyl-CoA:3-oxoacid coenzyme A transferase Acta Crystallogr. Sect. D 66 797-805 2010 Sus scrofa http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20606260&form=6&db=m 2.8.3.5 80975 The role of 3-oxo acid-CoA transferase in the regulation of ketogenesis in the liver FEBS Lett. 103 212-215 1979 Gallus gallus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=38142&form=6&db=m 2.8.3.5 80975 The role of 3-oxo acid-CoA transferase in the regulation of ketogenesis in the liver FEBS Lett. 103 212-215 1979 Clupea harengus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=38142&form=6&db=m 2.8.3.5 80975 The role of 3-oxo acid-CoA transferase in the regulation of ketogenesis in the liver FEBS Lett. 103 212-215 1979 Columba livia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=38142&form=6&db=m 2.8.3.5 80975 The role of 3-oxo acid-CoA transferase in the regulation of ketogenesis in the liver FEBS Lett. 103 212-215 1979 Oryctolagus cuniculus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=38142&form=6&db=m 2.8.3.5 80975 The role of 3-oxo acid-CoA transferase in the regulation of ketogenesis in the liver FEBS Lett. 103 212-215 1979 Dicentrarchus labrax http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=38142&form=6&db=m 2.8.3.5 80975 The role of 3-oxo acid-CoA transferase in the regulation of ketogenesis in the liver FEBS Lett. 103 212-215 1979 Lacerta viridis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=38142&form=6&db=m 2.8.3.5 80975 The role of 3-oxo acid-CoA transferase in the regulation of ketogenesis in the liver FEBS Lett. 103 212-215 1979 Mus musculus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=38142&form=6&db=m 2.8.3.5 80975 The role of 3-oxo acid-CoA transferase in the regulation of ketogenesis in the liver FEBS Lett. 103 212-215 1979 Oncorhynchus mykiss http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=38142&form=6&db=m 2.8.3.5 80975 The role of 3-oxo acid-CoA transferase in the regulation of ketogenesis in the liver FEBS Lett. 103 212-215 1979 Pleuronectes platessa http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=38142&form=6&db=m 2.8.3.5 80975 The role of 3-oxo acid-CoA transferase in the regulation of ketogenesis in the liver FEBS Lett. 103 212-215 1979 Raja clavata http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=38142&form=6&db=m 2.8.3.5 80975 The role of 3-oxo acid-CoA transferase in the regulation of ketogenesis in the liver FEBS Lett. 103 212-215 1979 Rattus norvegicus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=38142&form=6&db=m 2.8.3.5 80975 The role of 3-oxo acid-CoA transferase in the regulation of ketogenesis in the liver FEBS Lett. 103 212-215 1979 Scomber scombrus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=38142&form=6&db=m 2.8.3.5 80975 The role of 3-oxo acid-CoA transferase in the regulation of ketogenesis in the liver FEBS Lett. 103 212-215 1979 Scyliorhinus canicula http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=38142&form=6&db=m 2.8.3.5 645977 Turnover of succinyl-CoA:3-oxoacid CoA-transferase in glioma and neuroblastoma cells. Specific influence of acetoacetate in neuroblastoma cells Biochem. J. 224 67-74 1984 Mus musculus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6594997&form=6&db=m 2.8.3.5 645977 Turnover of succinyl-CoA:3-oxoacid CoA-transferase in glioma and neuroblastoma cells. Specific influence of acetoacetate in neuroblastoma cells Biochem. J. 224 67-74 1984 Rattus norvegicus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6594997&form=6&db=m