1.8.4.11 down enzyme expression is declined gradually when the plants are exposed to high salt, H2O2 and absisic acid conditions and decrease to lower level at 12 h 726436 1.8.4.11 down oxidative stress reduces the expression of the enzyme (MsrA) following treatment with 1-methyl-4-phenylpyridinium 764644 1.8.4.11 up astragaloside IV protects PC-12 cells from 1-methyl-4-phenylpyridinium-induced oxidative damage through upregulating MsrA. MsrA expression is dependent on the Sirt1-FOXO3a signaling pathway 764644 1.8.4.11 up induced expression under various stresses, regulated directly by the stress-responsive extracytoplasmic-function sigma factor SigH -, 741692 1.8.4.11 up msra-1 mRNA is increased by 2fold in daf-2 mutants compared to wild type controls when worms are cultured at 23 and 25°C, there is a notorious increase in MSRA-1 activity in daf-2 mutants as the worms age, at 23°C MSRA-1 expression is dramatically enhanced in the nervous system -, 695430 1.8.4.11 up serum anti-MSRA levels are significantly elevated in systemic sclerosis patients with pulmonary fibrosis, cardiac involvement, or decreased total antioxidant power compared with those without them 695897 1.8.4.11 up the expression is slightly up-regulated in a time-dependent manner after treatment with low temperature and drought within 12 h 726436 1.8.4.11 up the transcript level of isoform MSRA2 is significantly accumulated in both leaves and green fruits after ethephon treatment 726435 1.8.4.11 up the upstream (promoter 1) regulates the msrA1 transcript that codes for the mitochondrial form of MSRA, the downstream promoter (promoter 2) regulates the msrA2/3 transcripts that code for the cytosolic/nuclear forms of MSRA and is generally less active, both promoters are partially regulated by all-trans retinoic acid 698124