2.1.1.160	down	drought stress suppresses TCS gene expression in leaves	721123	
2.1.1.160	down	the expression of the enzyme is greatly decreased to 50% in the leaves of grafted tea leaves	734758	
2.1.1.160	additional information	amounts of transcripts are much higher in young leaf than in other parts of the plant. Larger amounts of transcripts are found in young calluses than in old tissues	701429	
2.1.1.160	additional information	caffeine synthase expression as well as caffeine content is found to be higher in commercially utilized tissues like apical bud, 1st leaf, 2nd leaf, young stem, and is lower in old leaf during non-dormant compared to dormant growth phase. Among fruit parts, fruit coats have higher caffeine synthase expression, caffeine content, and allantoin content	700125	
2.1.1.160	additional information	environmental stresses other than heavy metal stress and plant hormone treatments have no effect on the expression of TCS gene	721123	
2.1.1.160	additional information	expression is not altered by treatment with methyl jasmonate	-, 757997	
2.1.1.160	additional information	naturally occuring low-caffeine fruits have a lower expression of the theobromine synthase and caffeine synthase genes and also contain an extra transcript of the caffeine synthase gene encoding a mutant form. The absence of caffeine in these mutants probably results from a combination of transcriptional regulation and the presence of mutations	698115	
2.1.1.160	up	expression is increased in presence of 0.5 mM salicylic acid	-, 757997	
2.1.1.160	up	TCS transcript increases slightly on supply of a nitrogen source	721123