1.1.1.45 metabolism crucial enzyme in the non-phosphorylated sugar metabolism or glucuronate-xylulose pathway 760916 1.1.1.45 physiological function L-gulonate 3-dehydrogenase is a bifunctional dimeric protein that functions not only as an NAD+-dependent enzyme in the uronate cycle but also as a taxon-specific lambda-crystallin in rabbit lens 712765