1.14.14.115 evolution the enzyme belongs to the CYP716A subfamily of cytochrome P450 monooxygenases 746048 1.14.14.115 metabolism the beta-amyrin 11-oxidase gene CYP88D6 is the initial P450 gene in glycyrrhizin biosynthesis. CYP72A154 is responsible for C-30 oxidation of beta-amyrin in the glycyrrhizin pathway 716523 1.14.14.115 metabolism the enzyme is involved in the biosynthesis of glycyrrhizin 716523