1.1.1.237 3,4-dihydroxyphenylpyruvate + NADH + H+ - Coleus scutellarioides 3-(3,4-dihydroxyphenyl)lactate + NAD+ - ? 187866 1.1.1.237 3,4-dihydroxyphenylpyruvate + NADH + H+ - Coleus scutellarioides 3-(3,4-dihydroxyphenyl)lactate + NAD+ - r 187866 1.1.1.237 3,4-dihydroxyphenylpyruvate + NADPH + H+ - Coleus scutellarioides 3,4-dihydroxyphenyllactate + NADP+ - ? 371795 1.1.1.237 3,4-dihydroxyphenylpyruvate + NADPH + H+ - Coleus scutellarioides 3-(3,4-dihydroxyphenyl)lactate + NADP+ - r 425530 1.1.1.237 3-(4-hydroxyphenyl)lactate + NAD+ - Coleus scutellarioides 4-hydroxyphenylpyruvate + NADH + H+ - ? 369963 1.1.1.237 3-(4-hydroxyphenyl)lactate + NAD+ biosynthesis of rosmarinic acid Coleus scutellarioides 4-hydroxyphenylpyruvate + NADH + H+ - ? 369963 1.1.1.237 3-(4-hydroxyphenyl)pyruvate + NADH + H+ - Coleus scutellarioides 3-(4-hydroxyphenyl)lactate + NAD+ - ? 425537 1.1.1.237 3-(4-hydroxyphenyl)pyruvate + NADH + H+ - Coleus scutellarioides 3-(4-hydroxyphenyl)lactate + NAD+ - r 425537 1.1.1.237 3-(4-hydroxyphenyl)pyruvate + NADH + H+ - Salvia miltiorrhiza 3-(4-hydroxyphenyl)lactate + NAD+ - ? 425537 1.1.1.237 3-(4-hydroxyphenyl)pyruvate + NADH + H+ - Ocimum basilicum var. purpurascens 3-(4-hydroxyphenyl)lactate + NAD+ - ? 425537 1.1.1.237 3-(4-hydroxyphenyl)pyruvate + NADH + H+ - Perilla frutescens 3-(4-hydroxyphenyl)lactate + NAD+ - r 425537 1.1.1.237 3-(4-hydroxyphenyl)pyruvate + NADH + H+ - Salvia officinalis 3-(4-hydroxyphenyl)lactate + NAD+ - ? 425537 1.1.1.237 3-(4-hydroxyphenyl)pyruvate + NADPH + H+ - Coleus scutellarioides 3-(4-hydroxyphenyl)lactate + NADP+ - ? 424556 1.1.1.237 3-(4-hydroxyphenyl)pyruvate + NADPH + H+ substrate bindiing structure, docking study, overview Coleus scutellarioides 3-(4-hydroxyphenyl)lactate + NADP+ - r 424556 1.1.1.237 3-(4-hydroxyphenyl)pyruvate + NADPH + H+ - Arabidopsis thaliana (R)-3-(4-hydroxyphenyl)lactate + NADP+ - r 460089 1.1.1.237 3-(4-hydroxyphenyl)pyruvate + NADPH + H+ best substrate Arabidopsis thaliana (R)-3-(4-hydroxyphenyl)lactate + NADP+ - r 460089 1.1.1.237 3-(4-hydroxyphenyl)pyruvate + NADPH + H+ - Arabidopsis thaliana Col-0 (R)-3-(4-hydroxyphenyl)lactate + NADP+ - r 460089 1.1.1.237 3-(4-hydroxyphenyl)pyruvate + NADPH + H+ best substrate Arabidopsis thaliana Col-0 (R)-3-(4-hydroxyphenyl)lactate + NADP+ - r 460089 1.1.1.237 3-methoxy-4-hydroxyphenylpyruvate + NADH + H+ - Coleus scutellarioides 3-(3-methoxy-4-hydroxyphenyl)lactate + NAD+ - ? 187867 1.1.1.237 4-hydroxyphenylpyruvate + NADH + H+ - Coleus scutellarioides 3-(4-hydroxyphenyl)lactate + NAD+ - ? 187865 1.1.1.237 4-hydroxyphenylpyruvate + NADH + H+ - Coleus scutellarioides 3-(4-hydroxyphenyl)lactate + NAD+ - r 187865 1.1.1.237 4-hydroxyphenylpyruvate + NADPH + H+ - Coleus scutellarioides 4-hydroxyphenyllactate + NADP+ - r 370805 1.1.1.237 4-hydroxyphenylpyruvate + NADPH + H+ - Coleus scutellarioides 4-hydroxyphenyllactate + NADP+ - ? 370805 1.1.1.237 4-hydroxyphenylpyruvate + NADPH + H+ the enzyme is involved in L-serine biosynthesis and rosmarinic acid biosynthesis Coleus scutellarioides 4-hydroxyphenyllactate + NADP+ - ? 370805 1.1.1.237 4-hydroxyphenylpyruvate + NADPH + H+ part of the metabolic pathway leading to rosmarinic acid and lithospermic acid B Salvia miltiorrhiza 4-hydroxyphenyllactate + NADP+ - ? 370805 1.1.1.237 4-hydroxyphenylpyruvate + NADPH + H+ - Wickerhamia fluorescens D-(4-hydroxyphenyl)lactate + NADP+ - ? 426494 1.1.1.237 4-hydroxyphenylpyruvate + NADPH + H+ - Wickerhamia fluorescens TK1 D-(4-hydroxyphenyl)lactate + NADP+ - ? 426494 1.1.1.237 4-hydroxyphenylpyruvate + NADPH + H+ - Arabidopsis thaliana 3-(4-hydroxyphenyl)lactate + NADP+ - ? 459072 1.1.1.237 4-hydroxyphenylpyruvate + NADPH + H+ - Arabidopsis thaliana Col-0 3-(4-hydroxyphenyl)lactate + NADP+ - ? 459072 1.1.1.237 beta-phenylpyruvate + NADH + H+ - Coleus scutellarioides 2-hydroxy-3-phenylpropanoate + NAD+ - r 188247 1.1.1.237 glyoxylate + NADPH + H+ - Wickerhamia fluorescens glycolate + NADP+ - ? 394866 1.1.1.237 glyoxylate + NADPH + H+ - Wickerhamia fluorescens TK1 glycolate + NADP+ - ? 394866 1.1.1.237 hydroxypyruvate + NADH + H+ - Wickerhamia fluorescens D-glycerate + NAD+ - ? 397450 1.1.1.237 hydroxypyruvate + NADH + H+ - Wickerhamia fluorescens TK1 D-glycerate + NAD+ - ? 397450 1.1.1.237 hydroxypyruvate + NADPH + H+ - Arabidopsis thaliana D-glycerate + NADP+ - ? 394875 1.1.1.237 hydroxypyruvate + NADPH + H+ reaction of EC 1.1.1.81 Arabidopsis thaliana D-glycerate + NADP+ - ? 394875 1.1.1.237 hydroxypyruvate + NADPH + H+ reaction of EC 1.1.1.81 Arabidopsis thaliana Col-0 D-glycerate + NADP+ - ? 394875 1.1.1.237 hydroxypyruvate + NADPH + H+ - Arabidopsis thaliana Col-0 D-glycerate + NADP+ - ? 394875 1.1.1.237 additional information rosmarinic acid biosynthetic pathway is regulated by interactions of several enzymes necessary for biosynthesis including HPPR Coleus scutellarioides ? - ? 89 1.1.1.237 additional information no substrates: pyruvate, oxaloacetate or benzoylformate Wickerhamia fluorescens ? - ? 89 1.1.1.237 additional information isoform HPPR2 has both hydroxyphenylpyruvate reductase and hydroxypyruvate reductase activities Arabidopsis thaliana ? - - 89 1.1.1.237 additional information no substrates: pyruvate, oxaloacetate or benzoylformate Wickerhamia fluorescens TK1 ? - ? 89 1.1.1.237 additional information isoform HPPR2 has both hydroxyphenylpyruvate reductase and hydroxypyruvate reductase activities Arabidopsis thaliana Col-0 ? - - 89 1.1.1.237 phenylpyruvate + NADPH + H+ - Arabidopsis thaliana D-phenyllactate + NADP+ - ? 426932 1.1.1.237 phenylpyruvate + NADPH + H+ more than 99.9% D-isomer, L-isomer below limits of detection Wickerhamia fluorescens D-phenyllactate + NADP+ - ? 426932 1.1.1.237 phenylpyruvate + NADPH + H+ more than 99.9% D-isomer, L-isomer below limits of detection Wickerhamia fluorescens TK1 D-phenyllactate + NADP+ - ? 426932 1.1.1.237 phenylpyruvate + NADPH + H+ - Arabidopsis thaliana Col-0 D-phenyllactate + NADP+ - ? 426932 1.1.1.237 phenylpyruvate + NADPH + H+ - Arabidopsis thaliana phenyllactate + NADP+ - ? 459867 1.1.1.237 phenylpyruvate + NADPH + H+ - Arabidopsis thaliana Col-0 phenyllactate + NADP+ - ? 459867