1.14.11.55 (4S)-ectoine + 2-oxoglutarate + O2 - Virgibacillus salexigens (4S,5S)-5-hydroxyectoine + succinate + CO2 - ? 440036 1.14.11.55 ectoine + 2-oxoglutarate + O2 - Pseudomonas stutzeri 5-hydroxyectoine + succinate + CO2 - ir 438329 1.14.11.55 ectoine + 2-oxoglutarate + O2 - Streptomyces coelicolor 5-hydroxyectoine + succinate + CO2 - ? 438329 1.14.11.55 ectoine + 2-oxoglutarate + O2 - Nitrosopumilus maritimus 5-hydroxyectoine + succinate + CO2 - ? 438329 1.14.11.55 ectoine + 2-oxoglutarate + O2 - Virgibacillus salexigens 5-hydroxyectoine + succinate + CO2 - ? 438329 1.14.11.55 ectoine + 2-oxoglutarate + O2 - Virgibacillus salexigens 5-hydroxyectoine + succinate + CO2 - ir 438329 1.14.11.55 ectoine + 2-oxoglutarate + O2 - Sphingopyxis alaskensis 5-hydroxyectoine + succinate + CO2 - ? 438329 1.14.11.55 ectoine + 2-oxoglutarate + O2 - Sphingopyxis alaskensis 5-hydroxyectoine + succinate + CO2 - ir 438329 1.14.11.55 ectoine + 2-oxoglutarate + O2 - Halomonas elongata 5-hydroxyectoine + succinate + CO2 - ? 438329 1.14.11.55 ectoine + 2-oxoglutarate + O2 - Halomonas elongata 5-hydroxyectoine + succinate + CO2 - ir 438329 1.14.11.55 ectoine + 2-oxoglutarate + O2 - Paenibacillus lautus 5-hydroxyectoine + succinate + CO2 - ir 438329 1.14.11.55 ectoine + 2-oxoglutarate + O2 - Alkalilimnicola ehrlichii 5-hydroxyectoine + succinate + CO2 - ir 438329 1.14.11.55 ectoine + 2-oxoglutarate + O2 - Acidiphilium cryptum 5-hydroxyectoine + succinate + CO2 - ir 438329 1.14.11.55 ectoine + 2-oxoglutarate + O2 - Streptomyces anulatus 5-hydroxyectoine + succinate + CO2 - ? 438329 1.14.11.55 ectoine + 2-oxoglutarate + O2 - Virgibacillus halodenitrificans 5-hydroxyectoine + succinate + CO2 - ir 438329 1.14.11.55 ectoine + 2-oxoglutarate + O2 - Streptomyces cattleya 5-hydroxyectoine + succinate + CO2 - ? 438329 1.14.11.55 ectoine + 2-oxoglutarate + O2 - Stutzerimonas stutzeri 5-hydroxyectoine + succinate + CO2 - ? 438329 1.14.11.55 ectoine + 2-oxoglutarate + O2 - Virgibacillus salexigens 5-hydroxyectoine + succinate + CO2 reaction is dependent on iron(II), molecular oxygen, and 2-oxoglutarate ? 438329 1.14.11.55 ectoine + 2-oxoglutarate + O2 - Streptomyces coelicolor A3(2) 5-hydroxyectoine + succinate + CO2 - ? 438329 1.14.11.55 ectoine + 2-oxoglutarate + O2 - Stutzerimonas stutzeri A1501 5-hydroxyectoine + succinate + CO2 - ? 438329 1.14.11.55 ectoine + 2-oxoglutarate + O2 - Pseudomonas stutzeri A1501 5-hydroxyectoine + succinate + CO2 - ir 438329 1.14.11.55 ectoine + 2-oxoglutarate + O2 - Sphingopyxis alaskensis DSM 13593 5-hydroxyectoine + succinate + CO2 - ? 438329 1.14.11.55 ectoine + 2-oxoglutarate + O2 - Sphingopyxis alaskensis DSM 13593 5-hydroxyectoine + succinate + CO2 - ir 438329 1.14.11.55 ectoine + 2-oxoglutarate + O2 - Virgibacillus halodenitrificans PDB-F2 5-hydroxyectoine + succinate + CO2 - ir 438329 1.14.11.55 ectoine + 2-oxoglutarate + O2 - Halomonas elongata DSM 2581 5-hydroxyectoine + succinate + CO2 - ir 438329 1.14.11.55 ectoine + 2-oxoglutarate + O2 - Halomonas elongata DSM 2581 5-hydroxyectoine + succinate + CO2 - ? 438329 1.14.11.55 ectoine + 2-oxoglutarate + O2 - Streptomyces cattleya NBRC 14057 5-hydroxyectoine + succinate + CO2 - ? 438329 1.14.11.55 L-homoectoine + 2-oxoglutarate + O2 - Sphingopyxis alaskensis trans-5-hydroxy-L-homoectoine + succinate + CO2 - ? 462644 1.14.11.55 L-homoectoine + 2-oxoglutarate + O2 - Stutzerimonas stutzeri trans-5-hydroxy-L-homoectoine + succinate + CO2 - ? 462644 1.14.11.55 L-homoectoine + 2-oxoglutarate + O2 - Stutzerimonas stutzeri A1501 trans-5-hydroxy-L-homoectoine + succinate + CO2 - ? 462644 1.14.11.55 L-homoectoine + 2-oxoglutarate + O2 - Sphingopyxis alaskensis DSM 13593 trans-5-hydroxy-L-homoectoine + succinate + CO2 - ? 462644 1.14.11.55 L-proline + 2-oxoglutarate + O2 - Halomonas elongata trans-3-hydroxyproline + succinate + CO2 - ? 462651 1.14.11.55 L-proline + 2-oxoglutarate + O2 - Streptomyces cattleya trans-3-hydroxyproline + succinate + CO2 - ? 462651 1.14.11.55 L-proline + 2-oxoglutarate + O2 - Halomonas elongata DSM 2581 trans-3-hydroxyproline + succinate + CO2 - ? 462651 1.14.11.55 L-proline + 2-oxoglutarate + O2 - Streptomyces cattleya NBRC 14057 trans-3-hydroxyproline + succinate + CO2 - ? 462651 1.14.11.55 additional information ectoine hydroxylase operates exclusively in one direction under physiologically relevant conditions to direct the formation of 5-hydroxyectoine from the precursor ectoine Pseudomonas stutzeri ? - ? 89 1.14.11.55 additional information ectoine hydroxylase operates exclusively in one direction under physiologically relevant conditions to direct the formation of 5-hydroxyectoine from the precursor ectoine Virgibacillus salexigens ? - ? 89 1.14.11.55 additional information ectoine hydroxylase operates exclusively in one direction under physiologically relevant conditions to direct the formation of 5-hydroxyectoine from the precursor ectoine Sphingopyxis alaskensis ? - ? 89 1.14.11.55 additional information ectoine hydroxylase operates exclusively in one direction under physiologically relevant conditions to direct the formation of 5-hydroxyectoine from the precursor ectoine Halomonas elongata ? - ? 89 1.14.11.55 additional information ectoine hydroxylase operates exclusively in one direction under physiologically relevant conditions to direct the formation of 5-hydroxyectoine from the precursor ectoine Paenibacillus lautus ? - ? 89 1.14.11.55 additional information ectoine hydroxylase operates exclusively in one direction under physiologically relevant conditions to direct the formation of 5-hydroxyectoine from the precursor ectoine Alkalilimnicola ehrlichii ? - ? 89 1.14.11.55 additional information ectoine hydroxylase operates exclusively in one direction under physiologically relevant conditions to direct the formation of 5-hydroxyectoine from the precursor ectoine Acidiphilium cryptum ? - ? 89 1.14.11.55 additional information no substrate: L-proline Streptomyces coelicolor ? - ? 89 1.14.11.55 additional information the cosubstrate 2-oxoglutarate is stoichiometrically decarboxylated during the hydroxylation of the substrate ectoine. CO2 is thereby liberated from 2-oxoglutarate to form succinate. During the hydroxylation reaction, one atom of the atmospheric oxygen molecule is incorporated into succinate, whereas the other atom is incorporated into the hydroxy group formed on ectoine Virgibacillus salexigens ? - ? 89 1.14.11.55 additional information no substrate: L-proline Streptomyces coelicolor A3(2) ? - ? 89 1.14.11.55 additional information ectoine hydroxylase operates exclusively in one direction under physiologically relevant conditions to direct the formation of 5-hydroxyectoine from the precursor ectoine Pseudomonas stutzeri A1501 ? - ? 89 1.14.11.55 additional information ectoine hydroxylase operates exclusively in one direction under physiologically relevant conditions to direct the formation of 5-hydroxyectoine from the precursor ectoine Sphingopyxis alaskensis DSM 13593 ? - ? 89 1.14.11.55 additional information ectoine hydroxylase operates exclusively in one direction under physiologically relevant conditions to direct the formation of 5-hydroxyectoine from the precursor ectoine Halomonas elongata DSM 2581 ? - ? 89