2.5.1.29	Acute Lung Injury	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30652497&form=6&db=m	Inhibition of GGPPS1 attenuated LPS-induced acute lung injury and was associated with NLRP3 inflammasome suppression.	ongoing research,therapeutic application,unassigned	3,2,0	
2.5.1.29	Acute Lung Injury	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33729030&form=6&db=m	Geranylgeranyl diphosphate synthase deficiency hyperactivates macrophages and aggravates lipopolysaccharide-induced acute lung injury.	causal interaction,therapeutic application,unassigned	4,1,0	
2.5.1.29	Acute Lung Injury	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34530204&form=6&db=m	Geranylgeranyl diphosphate synthase 1 knockdown suppresses NLRP3 inflammasome activity via promoting autophagy in sepsis-induced acute lung injury.	causal interaction,diagnostic usage,ongoing research,therapeutic application	1,3,3,2	
2.5.1.29	Adenocarcinoma	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30918331&form=6&db=m	Inhibition of geranylgeranyl diphosphate synthase is a novel therapeutic strategy for pancreatic ductal adenocarcinoma.	causal interaction,therapeutic application,unassigned	4,4,0	
2.5.1.29	Adenocarcinoma of Lung	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29377583&form=6&db=m	Overexpression of geranylgeranyl diphosphate synthase contributes to tumour metastasis and correlates with poor prognosis of lung adenocarcinoma.	causal interaction,diagnostic usage,ongoing research,therapeutic application	4,4,4,2	
2.5.1.29	Ataxia	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31570763&form=6&db=m	Regulation of the Notch-ATM-abl axis by geranylgeranyl diphosphate synthase inhibition.	ongoing research,therapeutic application,unassigned	4,3,0	
2.5.1.29	Azoospermia	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31171774&form=6&db=m	The alteration of RhoA geranylgeranylation and Ras farnesylation breaks the integrity of the blood-testis barrier and results in hypospermatogenesis.	causal interaction,diagnostic usage,unassigned	3,1,0	
2.5.1.29	Bone Resorption	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21419634&form=6&db=m	Synthesis and biological evaluation of new 2-alkylaminoethyl-1,1-bisphosphonic acids against Trypanosoma cruzi and Toxoplasma gondii targeting farnesyl diphosphate synthase.	causal interaction,diagnostic usage,therapeutic application,unassigned	1,1,4,0	
2.5.1.29	Breast Neoplasms	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20480384&form=6&db=m	Geranylgeranyl diphosphate depletion inhibits breast cancer cell migration.	causal interaction,diagnostic usage,ongoing research,therapeutic application	3,1,3,4	
2.5.1.29	Breast Neoplasms	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21335425&form=6&db=m	Bisphosphonates Induce Autophagy by Depleting Geranylgeranyl Diphosphate.	diagnostic usage,ongoing research,therapeutic application,unassigned	1,1,1,0