4.2.99.20 D128A conserved among MenH proteins 702326 4.2.99.20 D210A decreased activity 685225 4.2.99.20 D210A kcat/Km is 9091fold lower than wild-type value 685225 4.2.99.20 D210A part of the catalytically essential triad 702326 4.2.99.20 F153A residue involved in open-closed transition, mutation leads to large decrease in enzymatic activity 730042 4.2.99.20 H232A decreased activity 685225 4.2.99.20 H232A kcat/Km is 208333fold lower than wild-type value 685225 4.2.99.20 H232A part of the catalytically essential triad 702326 4.2.99.20 H232K part of the catalytically essential triad 702326 4.2.99.20 K212A conserved among MenH proteins 702326