EC Number   |
Activating Compound  |
Reference |
|---|
   3.1.1.32 | 1-propanol |
stimulates phospholipase A1 activity and inhibits lysophospholipase 1 activity |
94317 |
| 3.1.1.32 | dithiothreitol |
- |
709425 |
| 3.1.1.32 | dithiothreitol |
required for full activity. Addition of 2 mM increases PLA1/2 activity 167fold |
709425 |
| 3.1.1.32 | more |
addition of bovine liver superoxide dismutase 1, SOD1, resultes in an increased rate of RP534-catalyzed phospholipid hydrolysis, mechanism, overview |
715386 |
| 3.1.1.32 | more |
endothelial lipase is upregulated by inflammation |
691842 |
| 3.1.1.32 | more |
NO2 specifically reacts with the plasma membrane component of pulmonary artery endothelial cells, causing specific activation of the enzyme |
94328 |
| 3.1.1.32 | more |
purified H-Rev107 exhibits an 88fold higher PLA1/2 activity than the cytosolic fraction |
709425 |
| 3.1.1.32 | more |
TbPLA1 does not require metal cofactors for activity, but it does require interfacial activation prior to catalysis, activation by Triton X-100/glycerophosphatidylcholine mixed micelle surfaces is not specific and does not require the preformation of a specific enzyme-substrate complex to achieve surface binding, activation kinetics and mechanism, overview |
678064 |
| 3.1.1.32 | more |
the enzyme is activated by the binding of isoprenaline to beta2-adrenergic receptors |
94325 |
| 3.1.1.32 | Rab22 |
a guanine nucleotide binding protein, activates the VipD phospholipase A1, C-terminal binding |
730833 |
