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EC Number
Activating Compound
Commentary
Reference
1.1.1.145
flutamide
increase in mRNA expression in testis
688664
1.1.1.145
iodoacetamide
-
389374
1.1.1.145
more
3beta-HSD mRNA level significantly increases in Leydig cells of corticosterone-deficient rats and simultaneous corticosterone treatment completely maintains the expression at control levels
699111
1.1.1.145
more
hypoxia-inducible factor-1alpha potentially regulates 3beta-hydroxysteroid dehydrogenase type 1 promoter activity in Leydig cells
698503
1.1.1.145
p-chloromercuribenzoate
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389374
1.1.1.145
testosterone
at low dose, increase in mRNA expression. At doses above 0.2 mg/kg/day, downregulation of 3beta-hydroxysteroid dehydrogenase mRNA
688664
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