EC Number |
Activating Compound |
Reference |
---|
1.14.14.139 | more |
feeding of cholic acid, taurine, or cholesterol does not affect expression of CYP8B1 |
675742 |
1.14.14.139 | more |
feeding of taurine alone has no effect on enzyme expression |
675742 |
1.14.14.139 | more |
hepatocyte nuclear factor 4a strongly induces the enzyme, the enzyme expression is induced by soybean isoflavones, e.g. genistein, daidzein, and glycitein, in both female and male mice, intake of soy isoflavones plus fenofibrate does not increase CYP8B1 mRNA levels in females, whereas there was an obvious upregulation in males, presence of PPARa inhibits isoflavone upregulation of CYP8B1 in cotransfected HepG2 cells, mechanism modeling, overview |
688559 |
1.14.14.139 | more |
hepatocyte nuclear factor 4a strongly induces the enzyme, the enzyme expression is induced by soybean isoflavones, e.g. genistein, daidzein, and glycitein, presence of PPARa inhibits isoflavone upregulation of CYP8B1 in cotransfected HepG2 cells, mechanism modeling, overview |
688559 |
1.14.14.139 | more |
NADPH-cytochrome P-450 reductase, EC 1.6.2.4, is required for maximal activity |
659116, 659123 |